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  4. Recombinant Human Transcription factor YY2 (YY2)

Recombinant Human Transcription factor YY2 (YY2)

  • 中文名称：
    人YY2重组蛋白
  • 货号：
    CSB-YP026299HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人YY2重组蛋白
  • 货号：
    CSB-EP026299HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人YY2重组蛋白
  • 货号：
    CSB-EP026299HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人YY2重组蛋白
  • 货号：
    CSB-BP026299HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人YY2重组蛋白
  • 货号：
    CSB-MP026299HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    YY2
  • Uniprot No.：
  • 别名：
    Transcription factor yin yang 2; Transcription factor YY2; TYY2_HUMAN; Yin and yang 2; YY-2; Yy2; YY2 transcription factor; Zinc finger protein 631; ZNF631
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-372
  • 氨基酸序列
    MASNEDFSIT QDLEIPADIV ELHDINVEPL PMEDIPTESV QYEDVDGNWI YGGHNHPPLM VLQPLFTNTG YGDHDQEMLM LQTQEEVVGY CDSDNQLGND LEDQLALPDS IEDEHFQMTL ASLSASAAST STSTQSRSKK PSKKPSGKSA TSTEANPAGS SSSLGTRKWE QKQMQVKTLE GEFSVTMWSP NDNNDQGAVG EGQAENPPDY SEYLKGKKLP PGGLPGIDLS DPKQLAEFTK VKPKRSKGEP PKTVPCSYSG CEKMFRDYAA MRKHLHIHGP RVHVCAECGK AFLESSKLRR HQLVHTGEKP FQCTFEGCGK RFSLDFNLRT HLRIHTGDKP FVCPFDVCNR KFAQSTNLKT HILTHVKTKN NP
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Functions as a multifunctional transcription factor that may exhibit positive and negative control on a large number of genes. May antagonize YY1 and function in development and differentiation.
  • 基因功能参考文献：
    1. In human colorectal cancer metastases to the liver, the levels of AES protein are correlated with those of YY2 PMID: 27561171
    2. article summarizes all critical aspects that are (or will be) relevant for a better understanding of YY1- and/or YY2-mediated cellular control mechanisms PMID: 22248057
    3. Results show that human YY2 is not redundant to YY1, and YY2 is a significant regulator of genes previously identified as uniquely responding to YY1. PMID: 20215434
    4. YY2 can bind to and regulate some promoters known to be controlled by YY1. Similar to YY1, YY2 contains both transcriptional activation and repression functions. PMID: 15087442
    5. the novel factor YY2 antagonizes the negative actions exerted by YY1 PMID: 16260628
    6. yy2 expression is mediated by its own methylation-sensitive promoter. PMID: 19026728

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  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    YY transcription factor family
  • 组织特异性：
    Expressed in kidney, liver, spleen and testis but not in colon.
  • 数据库链接：

    HGNC: 31684

    OMIM: 300570

    KEGG: hsa:404281

    STRING: 9606.ENSP00000389381

    UniGene: Hs.673601