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  4. Recombinant Human Transmembrane protease serine 11E (TMPRSS11E), partial

Recombinant Human Transmembrane protease serine 11E (TMPRSS11E), partial

  • 中文名称：
    人TMPRSS11E重组蛋白
  • 货号：
    CSB-YP892142HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人TMPRSS11E重组蛋白
  • 货号：
    CSB-EP892142HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人TMPRSS11E重组蛋白
  • 货号：
    CSB-EP892142HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人TMPRSS11E重组蛋白
  • 货号：
    CSB-BP892142HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人TMPRSS11E重组蛋白
  • 货号：
    CSB-MP892142HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    TMPRSS11E
  • Uniprot No.：
  • 别名：
    TMPRSS11E; DESC1; TMPRSS11E2; UNQ742/PRO1461; Transmembrane protease serine 11E; EC 3.4.21.-; Serine protease DESC1; Transmembrane protease serine 11E2) [Cleaved into: Transmembrane protease serine 11E non-catalytic chain; Transmembrane protease serine 11E catalytic chain]
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Serine protease which possesses both gelatinolytic and caseinolytic activities. Shows a preference for Arg in the P1 position.
  • 基因功能参考文献：
    1. DESC1 may suppress esophageal squamous cell carcinoma development by sensitizing cells to apoptosis under an apoptotic stimulus through downregulating the EGFR/AKT signaling pathway. PMID: 26856390
    2. study demonstrates that two cellular serine proteases, DESC1 and MSPL, activate influenza viruses and emerging coronaviruses in cell culture and, because of their expression in human lung tissue, might promote viral spread in the infected host PMID: 25122802
    3. The domain of DESC1 exhibits a trypsin-like serine proteinase fold with a thrombin-like S1 pocket, a urokinase-type plasminogen activator-type S2 pocket, to accept small residues, and an open hydrophobic S3/S4 cavity to accept large hydrophobic residues. PMID: 17388811
  • 亚细胞定位：
    Cell membrane; Single-pass type II membrane protein.; [Transmembrane protease serine 11E catalytic chain]: Secreted.
  • 蛋白家族：
    Peptidase S1 family
  • 组织特异性：
    Expression can only be detected in tissues derived from the head and neck, and in skin, prostate and testis.
  • 数据库链接：

    HGNC: 24465

    OMIM: 610399

    KEGG: hsa:28983

    STRING: 9606.ENSP00000307519

    UniGene: Hs.201877