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  4. Recombinant Human Transmembrane protein 107 (TMEM107), partial

Recombinant Human Transmembrane protein 107 (TMEM107), partial

  • 中文名称：
    人TMEM107重组蛋白
  • 货号：
    CSB-YP023676HU1
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人TMEM107重组蛋白
  • 货号：
    CSB-EP023676HU1
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人TMEM107重组蛋白
  • 货号：
    CSB-EP023676HU1-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人TMEM107重组蛋白
  • 货号：
    CSB-BP023676HU1
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人TMEM107重组蛋白
  • 货号：
    CSB-MP023676HU1
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    TMEM107
  • Uniprot No.：
  • 别名：
    TMEM107; DC20; UNQ638/PRO1268; Transmembrane protein 107
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Plays a role in cilia formation and embryonic patterning. Requires for normal Sonic hedgehog (Shh) signaling in the neural tube and acts in combination with GLI2 and GLI3 to pattern ventral and intermediate neuronal cell types. During ciliogenesis regulates the ciliary transition zone localization of some MKS complex proteins.
  • 基因功能参考文献：
    1. This study shows that known MKS loci account for the overwhelming majority of MKS cases but additional loci exist including MKS13 caused by TMEM107 mutation. PMID: 26123494
    2. TMEM107 (2810049P21Rik) is a strong candidate gene for central areolar choroidal dystrophy, CACD (human 17p13). Conclusion is based on a massive expression data set for mouse (103 strains in GeneNetwork.org) and joint analysis of RetNet database. PMID: 19727342
  • 相关疾病：
    Meckel syndrome 13 (MKS13); Orofaciodigital syndrome 16 (OFD16)
  • 亚细胞定位：
    Membrane; Multi-pass membrane protein. Cell projection, cilium.
  • 数据库链接：

    HGNC: 28128

    OMIM: 616183

    KEGG: hsa:84314

    UniGene: Hs.513933