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  4. Recombinant Human Zinc transporter ZIP13 (SLC39A13), partial

Recombinant Human Zinc transporter ZIP13 (SLC39A13), partial

  • 中文名称：
    人SLC39A13重组蛋白
  • 货号：
    CSB-YP850305HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人SLC39A13重组蛋白
  • 货号：
    CSB-EP850305HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人SLC39A13重组蛋白
  • 货号：
    CSB-EP850305HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人SLC39A13重组蛋白
  • 货号：
    CSB-BP850305HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人SLC39A13重组蛋白
  • 货号：
    CSB-MP850305HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    SLC39A13
  • Uniprot No.：
  • 别名：
    FLJ25785; LIV-1 subfamily of ZIP zinc transporter 9; LZT-Hs9; S39AD_HUMAN; SLC39A13; solute carrier family 39 (metal ion transporter), member 13; solute carrier family 39 (zinc transporter), member 13; Solute carrier family 39 member 13; Zinc transporter ZIP13; ZIP-13; Zrt- and Irt-like protein 13
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Acts as a zinc-influx transporter.
  • 基因功能参考文献：
    1. The spondylocheiro dysplastic form of Ehlers-Danlos syndrome, in which ZIP13 is defective, is likely due to a failure of iron delivery to the secretory compartments. PMID: 25006035
    2. s demonstrated that both the ZIP13(G64D) and ZIP13(DeltaFLA) protein levels are decreased by degradation via the valosin-containing protein (VCP)-linked ubiquitin proteasome pathway. PMID: 25007800
    3. human ZIP13 releases zinc from vesicular stores PMID: 23213233
    4. Biochemical characterization of human ZIP13 protein: a homo-dimerized zinc transporter involved in the spondylocheiro dysplastic Ehlers-Danlos syndrome. PMID: 21917916
    5. mutations in the SLC39A13 gene do not account for the Ehlers-Danlos syndrome type VIB phenotype PMID: 21739577
    6. clinical features of 6 patients from 2 consanguineous families with Ehlers-Danlos syndrome-like features caused by a mutation in the zinc transporter gene SLC39A13 PMID: 18513683

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  • 相关疾病：
    Ehlers-Danlos syndrome-like spondylocheirodysplasia (SCD-EDS)
  • 亚细胞定位：
    Golgi apparatus membrane; Multi-pass membrane protein.
  • 蛋白家族：
    ZIP transporter (TC 2.A.5) family
  • 数据库链接：

    HGNC: 20859

    OMIM: 608735

    KEGG: hsa:91252

    STRING: 9606.ENSP00000354689

    UniGene: Hs.523664