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  4. Recombinant Human herpesvirus 1 Tegument protein UL51 (UL51)

Recombinant Human herpesvirus 1 Tegument protein UL51 (UL51)

  • 货号：
    CSB-YP318026HWY
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP318026HWY
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP318026HWY-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP318026HWY
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP318026HWY
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    UL51
  • Uniprot No.：
  • 别名：
    UL51; Tegument protein UL51
  • 种属：
    Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-244
  • 氨基酸序列
    MASLLGAICG WGARPEEQYE MIRAAVPPSE AEPRLQEALA VVNALLPAPI TLDDALGSLD DTRRLVKARA LARTYHACMV NLERLARHHP GFEAPTIDGA VAAHQDKMRR LADTCMATIL QMYMSVGAAD KSADVLVSQA IRSMAESDVV MEDVAIAERA LGLSAFGVAG GTRSGGIGVT EAPSLGHPHT PPPEVTLAPA ARNGDALPDP KPESCPRVSV PRPTASPTAP RPGPSRAAPC VLGQ
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Plays several roles during the time course of infection, including egress of virus particles from the perinuclear space and secondary envelopment of cytoplasmic capsids that bud into specific trans-Golgi network (TGN)-derived membranes. Plays also an essential role in the maintenance of host cytoplasmic viral assembly center (cVAC) morphology in primary host neuronal cells.
  • 基因功能参考文献：
    1. This is the first report to identify the mechanism by which UL51 is regulated as well as the significance of UL51 phosphorylation in HSV-1 infection. Our study may provide insights into the regulatory mechanisms of other herpesviral UL51 homologs. PMID: 29976672
    2. UL51 protein interacts with the UL7 protein and plays a role in its recruitment into the virion. PMID: 25552711
    3. UL51 has an important role in cell-to-cell spread in addition to it role in virus assembly. PMID: 24453372
    4. UL51 protein is involved in the maturation and egress of HSV-1 virus particles downstream of the initial envelopment step. PMID: 15890934
  • 亚细胞定位：
    Virion tegument. Host cytoplasm. Host Golgi apparatus.
  • 蛋白家族：
    Herpesviridae UL51 family
  • 数据库链接：

    KEGG: vg:2703422