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  4. Recombinant Human herpesvirus 6A DNA polymerase processivity factor (U27)

Recombinant Human herpesvirus 6A DNA polymerase processivity factor (U27)

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  • 中文名称：
    Recombinant Human herpesvirus 6A DNA polymerase processivity factor(U27)
  • 货号：
    CSB-YP346759HJZ
  • 规格：
    ￥2208
  • 图片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他：

产品详情

  • 纯度：
    Greater than 90% as determined by SDS-PAGE.
  • 基因名：
    U27
  • Uniprot No.：
  • 别名：
    U27; EPLF1DNA polymerase processivity factor; Phosphoprotein P41; PP41; Polymerase accessory protein; PAP
  • 种属：
    Human herpesvirus 6A (strain Uganda-1102) (HHV-6 variant A) (Human B lymphotropic virus)
  • 蛋白长度：
    Full Length
  • 来源：
    Yeast
  • 分子量：
    46.8 kDa
  • 表达区域：
    1-393aa
  • 氨基酸序列
    MCWSFHLFFKAHKARVGARTSFLTEMERGSRDHHRDHRDHREHRETREPPTLAFHMKSWKTINKSLKAFAKLLKENTTVTFTPQPSIIIQSAKNHLVQKLTIQAECLFLSDTDRFLTKTINNHIPLFESFMNIISNPEVTKMYIQHDSDLYTRVLVTASDTCTQASVPCVHGQEVVRDTGRSPLRIDLDHSTVSDVLKWLSPVTKTKRSGKSDALMAHIIVQVNPPTIKFVTEMNELEFSNSNKVIFYDVKNMRFNLSAKNLQQALSMCAVIKTSCSLRTVAAKDCKLILTSKSTLLTVEAFLTQEQLKEESRFERMGKQDDGKGDRSHKNDDGSALASKQEMQYKITNYMVPAKNGTAGSSLFNEKEDSESDDSMHFDYSSNPNPKRQRCVV
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 6xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Tris-based buffer,50% glycerol
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    3-7 business days
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 产品描述：

    Like all recombinant proteins, this Recombinant HHV-6 variant A U27 protein was encoded by recombinant DNA. The recombinant DNA was introduced to a plasmid in which the gene of U27 was cloned downstream of a promoter region. When the plasmid was introduced to the cells of Yeast, the Yeast’s own protein synthesis pathways would then result in the expression of the U27 protein. And the next step was protein purification. The purity of this recombinant protein is 90%+ determined by SDS-PAGE.

    Human herpesvirus 6A is a member of the genus Roseolovirus and the subfamily Betaherpesvirinae. HHV-6A encodes a 41-kDa nuclear phosphoprotein, U27, which acts as a processivity factor in the replication of the viral DNA. HHV-6A U27 has 43% amino acid sequence homology with HCMV UL44, which is important for DNA replication. n. A previous study on HHV-6A U27 revealed that it greatly increases the in vitro DNA synthesis activity of HHV-6A DNA polymerase. U27-deficient HHV-6A mutant (HHV-6ABACU27mut) with a frameshift insertion at the U27 gene using an HHV-6A bacterial artificial chromosome (BAC) system. U27 is essential for the reconstitution of the viral life cycle of HHV-6A.

  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Accessory subunit of the DNA polymerase that acts to increase the processivity of polymerization.
  • 蛋白家族：
    Herpesviridae polymerase accessory protein family