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  4. Recombinant Human immunodeficiency virus type 1 group M subtype B Virion infectivity factor (vif)

Recombinant Human immunodeficiency virus type 1 group M subtype B Virion infectivity factor (vif)

  • 货号：
    CSB-YP356666HLC
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP356666HLC
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP356666HLC-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP356666HLC
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP356666HLC
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    vif
  • Uniprot No.：
  • 别名：
    vifVirion infectivity factor; Vif; SOR protein) [Cleaved into: p17; p7]; Fragment
  • 种属：
    Human immunodeficiency virus type 1 group M subtype B (isolate SC) (HIV-1)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-109
  • 氨基酸序列
    GVSIEWTKKR YSTQVDPDLA DRLIHLYYFD CFSESAIRNA ILGALVSGRC EYQAGHNKVG SLQYLALTAL ITPKKTKPPL PSVRKLTEDR WNKPQKTKGH RGSHTMNGH
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Counteracts the innate antiviral activity of APOBEC3G. Forms a complex with host APOBEC3G thus preventing the entry of this lethally hypermutating enzyme into progeny virions. Functions as an adapter molecule, recruiting APOBEC3G to the ubiquitin-proteasome machinery. Targets APOBEC3G for degradation through the assembly with elongin BC complex, CUL5 and RBX1. Binds viral RNA and affects the stability of viral nucleoprotein core. May play a role in viral morphology. Interacts with host ABCE1, which seems to be involved in lentiviruses capsid formation and displays RNase L inhibitor activity. This interaction may play a role in protecting viral RNA from damage during viral assembly. May interact with host SAT, which is a regulator of polyamine cell level. This interaction may be relevant since polyamines affect viral RNA properties.
  • 亚细胞定位：
    Host cytoplasm. Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Virion.
  • 蛋白家族：
    Primate lentivirus group Vif protein family