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  4. Recombinant Human snRNA-activating protein complex subunit 1 (SNAPC1)

Recombinant Human snRNA-activating protein complex subunit 1 (SNAPC1)

  • 中文名称：
    人SNAPC1重组蛋白
  • 货号：
    CSB-YP623083HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人SNAPC1重组蛋白
  • 货号：
    CSB-EP623083HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人SNAPC1重组蛋白
  • 货号：
    CSB-EP623083HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人SNAPC1重组蛋白
  • 货号：
    CSB-BP623083HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人SNAPC1重组蛋白
  • 货号：
    CSB-MP623083HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    SNAPC1
  • Uniprot No.：
  • 别名：
    Proximal sequence element-binding transcription factor subunit gamma; PSE binding factor subunit gamma; PSE-binding factor subunit gamma; PTF subunit gamma; PTFgamma; Small nuclear RNA activating complex polypeptide 1; small nuclear RNA activating complex, polypeptide 1, 43kDa; Small nuclear RNA-activating complex polypeptide 1; Small nuclear RNA-activating protein complex, 43-KD subunit; SNAP43; SNAPc 43 kDa subunit; SNAPc subunit 1; Snapc1; SNPC1_HUMAN; snRNA activating protein complex 43 kDa subunit; snRNA activating protein complex subunit 1; snRNA-activating protein complex 43 kDa subunit; snRNA-activating protein complex subunit 1
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-368
  • 氨基酸序列
    MGTPPGLQTD CEALLSRFQE TDSVRFEDFT ELWRNMKFGT IFCGRMRNLE KNMFTKEALA LAWRYFLPPY TFQIRVGALY LLYGLYNTQL CQPKQKIRVA LKDWDEVLKF QQDLVNAQHF DAAYIFRKLR LDRAFHFTAM PKLLSYRMKK KIHRAEVTEE FKDPSDRVMK LITSDVLEEM LNVHDHYQNM KHVISVDKSK PDKALSLIKD DFFDNIKNIV LEHQQWHKDR KNPSLKSKTN DGEEKMEGNS QETERCERAE SLAKIKSKAF SVVIQASKSR RHRQVKLDSS DSDSASGQGQ VKATRKKEKK ERLKPAGRKM SLRNKGNVQN IHKEDKPLSL SMPVITEEEE NESLSGTEFT ASKKRRKH
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.
  • 基因功能参考文献：
    1. Results from a study on gene expression variability markers in early-stage human embryos shows that is a putative expression variability marker as well as a differential gene expression marker for the 3-day, 8-cell embryo stage. PMID: 26288249
    2. SNAPC1 is a general transcriptional coactivator that functions through elongating RNAPII. PMID: 22966203
    3. CK2 may have the capacity to differentially regulate U1 and U6 transcription even though SNAP(C) is universally utilized for human snRNA gene transcription [SNAPC protein, also called PTF or PSE-binding transcription factor] PMID: 15955816
  • 亚细胞定位：
    Nucleus.
  • 数据库链接：

    HGNC: 11134

    OMIM: 600591

    KEGG: hsa:6617

    STRING: 9606.ENSP00000216294

    UniGene: Hs.179312