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  4. Recombinant Human tRNA-specific adenosine deaminase 2 (ADAT2)

Recombinant Human tRNA-specific adenosine deaminase 2 (ADAT2)

  • 货号：
    CSB-YP767210HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP767210HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP767210HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP767210HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP767210HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    ADAT2
  • Uniprot No.：
  • 别名：
    adat2; ADAT2_HUMAN; Adenosine deaminase tRNA specific 2; Adenosine deaminase tRNA specific 2 TAD2 homolog; DEADC1; Deaminase domain containing 1; Deaminase domain containing protein 1; Deaminase domain-containing protein 1; dJ20N2; dJ20N2.1; TAD2; tRNA specific adenosine 34 deaminase subunit ADAT2; tRNA specific adenosine deaminase 2; tRNA specific adenosine deaminase 2 homolog; tRNA-specific adenosine deaminase 2; tRNA-specific adenosine-34 deaminase subunit ADAT2
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-191
  • 氨基酸序列
    MEAKAAPKPA ASGACSVSAE ETEKWMEEAM HMAKEALENT EVPVGCLMVY NNEVVGKGRN EVNQTKNATR HAEMVAIDQV LDWCRQSGKS PSEVFEHTVL YVTVEPCIMC AAALRLMKIP LVVYGCQNER FGGCGSVLNI ASADLPNTGR PFQCIPGYRA EEAVEMLKTF YKQENPNAPK SKVRKKECQK S
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Probably participates in deamination of adenosine-34 to inosine in many tRNAs.
  • 基因功能参考文献：
    1. Transfer RNAs (tRNAs) are among the most heavily modified RNA species. Data confirm that ADAT2 exhibits substrate specificity that includes tRNA(Ala-AGC) and tRNA(Thr-AGU), deaminating adenosine-34 to inosine-34 as post-transcriptional modifications. PMID: 28703578
    2. data indicate that ATAD2 overexpression in somatic cells, by acting on basic properties of chromatin, may contribute to malignant transformation PMID: 20581866
  • 蛋白家族：
    Cytidine and deoxycytidylate deaminase family, ADAT2 subfamily
  • 数据库链接：

    HGNC: 21172

    OMIM: 615388

    KEGG: hsa:134637

    STRING: 9606.ENSP00000237283

    UniGene: Hs.709561