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Recombinant Monodelphis domestica Cyclin-dependent kinase inhibitor 2A (CDKN2A)

  • 中文名称：
    Recombinant Monodelphis domestica Cyclin-dependent kinase inhibitor 2A(CDKN2A),Yeast
  • 货号：
    CSB-YP005089MUE
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Monodelphis domestica Cyclin-dependent kinase inhibitor 2A(CDKN2A),Yeast
  • 货号：
    CSB-EP005089MUE
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Monodelphis domestica Cyclin-dependent kinase inhibitor 2A(CDKN2A),Yeast
  • 货号：
    CSB-EP005089MUE-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Monodelphis domestica Cyclin-dependent kinase inhibitor 2A(CDKN2A),Yeast
  • 货号：
    CSB-BP005089MUE
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Monodelphis domestica Cyclin-dependent kinase inhibitor 2A(CDKN2A),Yeast
  • 货号：
    CSB-MP005089MUE
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    CDKN2ACyclin-dependent kinase inhibitor 2A; Cyclin-dependent kinase 4 inhibitor A; CDK4I; Tumor suppressor CDKN2A; p16-INK4a; p16-INK4
  • 种属：
    Monodelphis domestica (Gray short-tailed opossum)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-171
  • 氨基酸序列
    MGIVEKKEGG LERNRALFNS EGSCEGAKCG KEASMHTKHE SEESFSGEKL TEAAARGRTE VVTELLELGT NPNAVNRFGR SAIQVMMMGN VRLAAILLQY GAEPNTPDPT TLTLPVHDAA REGFLDTLML LHRAGARLDV RDSWGRLPVD LAEEQGHHLV VAYLREVVRD A
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.
  • 基因功能参考文献：
    1. Variations confer impaired glucose- and tolbutamide-induced insulin release in middle-aged and young healthy subjects. PMID: 17827400
  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    CDKN2 cyclin-dependent kinase inhibitor family
  • 组织特异性：
    Expressed predominantly in lung and testis. In the testis, restricted to germ cells in the seminiferous epithelium. Not detected in premeiotic spermatogonia but high levels found in postmeiotic spermatids. In primary tumors, low levels detected in melanoc
  • 数据库链接：

    STRING: 13616.ENSMODP00000004687

    UniGene: Mdm.219