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Recombinant Mouse Aspartoacylase-2 (Acy3)

  • 中文名称：
    Recombinant Mouse Aspartoacylase-2(Acy3),Yeast
  • 货号：
    CSB-YP856316MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Mouse Aspartoacylase-2(Acy3),Yeast
  • 货号：
    CSB-EP856316MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Mouse Aspartoacylase-2(Acy3),Yeast
  • 货号：
    CSB-EP856316MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Mouse Aspartoacylase-2(Acy3),Yeast
  • 货号：
    CSB-BP856316MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Mouse Aspartoacylase-2(Acy3),Yeast
  • 货号：
    CSB-MP856316MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Acy3
  • Uniprot No.：
  • 别名：
    Acy3; Aspa2N-acyl-aromatic-L-amino acid amidohydrolase; carboxylate-forming; EC 3.5.1.114; Acylase III; Aminoacylase III; AAIII; Aminoacylase-3; ACY-3; Aspartoacylase-2; Hepatitis C virus core-binding protein 1; HCBP1
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-318
  • 氨基酸序列
    MSSLPGSREP LLRVAVTGGT HGNEMCGVYL ARYWLQNPGE LQRPSFSAMP VLANPAATAA CCRYLDRDLN RSCTLTFLGS TATPDDPYEV KRARELNQLL GPKGTGQAFD FTLDLHNTTA NTGVCLISES NISFNLHLCH YLQRQNPGMP CRLFLYEPAG TETFSVESIS KNGICLEMGP QPQGVLRADL FSRMRALVAS ILDFIELFNQ GMDLPAFEMD IYRNLGSVDF PRTADGDLAG TVHPQLQDHD FEPLRPGEPI FKLFSGEDVL YEGDSIVYPV FINEAAYYEK HVAFLKSEKI RVTVPALLRL TPRSTQTP
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids.
  • 基因功能参考文献：
    1. Aminoacylase 3 binds to and cleaves the N-terminus of the hepatitis C virus that may by implicated in HCV pathogenesis. PMID: 23010594
    2. structures, in conjunction with biochemical data, indicated that AA3 mediates substrate specificity through van der Waals interactions providing a dynamic interaction interface, which facilitates a diverse range of substrates PMID: 20921362
    3. data suggest that in kidney proximal tubules, aminoacylase III plays an important role in deacetylating mercapturic acids PMID: 14656720
    4. A 16A resolution model of the AAIII dimer. PMID: 17434493
  • 亚细胞定位：
    Apical cell membrane; Peripheral membrane protein. Cytoplasm. Note=Predominantly localized in the apical membrane of cells in the S1 segment. In the proximal straight tubules (S2 and S3 segments) is expressed diffusely throughout the cytoplasm.
  • 蛋白家族：
    AspA/AstE family, Aspartoacylase subfamily
  • 组织特异性：
    Expressed predominantly in kidney and to a lesser extent in liver. Weakly expressed in heart, small intestine, brain, lung, testis, and stomach.
  • 数据库链接：

    KEGG: mmu:71670

    STRING: 10090.ENSMUSP00000050056

    UniGene: Mm.29735