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  4. Recombinant Mouse Bile acid-CoA:amino acid N-acyltransferase (Baat)

Recombinant Mouse Bile acid-CoA:amino acid N-acyltransferase (Baat)

  • 中文名称：
    Recombinant Mouse Bile acid-CoA:amino acid N-acyltransferase(Baat),Yeast
  • 货号：
    CSB-YP838692MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Mouse Bile acid-CoA:amino acid N-acyltransferase(Baat),Yeast
  • 货号：
    CSB-EP838692MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Mouse Bile acid-CoA:amino acid N-acyltransferase(Baat),Yeast
  • 货号：
    CSB-EP838692MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Mouse Bile acid-CoA:amino acid N-acyltransferase(Baat),Yeast
  • 货号：
    CSB-BP838692MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Mouse Bile acid-CoA:amino acid N-acyltransferase(Baat),Yeast
  • 货号：
    CSB-MP838692MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Baat
  • Uniprot No.：
  • 别名：
    BaatBile acid-CoA:amino acid N-acyltransferase; BACAT; BAT; EC 2.3.1.65; Bile acid-CoA thioesterase; Choloyl-CoA hydrolase; EC 3.1.2.27; Glycine N-choloyltransferase; Long-chain fatty-acyl-CoA hydrolase; EC 3.1.2.2
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-420
  • 氨基酸序列
    MAKLTAVPLS ALVDEPVHIQ VTGLAPFQVV CLQASLKDEK GNLFSSQAFY RASEVGEVDL EHDPSLGGDY MGVHPMGLFW SLKPEKLLGR LIKRDVMNSP YQIHIKACHP YFPLQDIVVS PPLDSLTLER WYVAPGVKRI QVKESRIRGA LFLPPGEGPF PGVIDLFGGA GGLMEFRASL LASRGFATLA LAYWNYDDLP SRLEKVDLEY FEEGVEFLLR HPKVLGPGVG ILSVCIGAEI GLSMAINLKQ IRATVLINGP NFVSQSPHVY HGQVYPPVPS NEEFVVTNAL GLVEFYRTFQ ETADKDSKYC FPIEKAHGHF LFVVGEDDKN LNSKVHANQA IAQLMKNGKK NWTLLSYPGA GHLIEPPYTP LCQASRMPIL IPSLSWGGEV IPHAAAQEHS WKEIQKFLKQ HLLPDLSSQL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Catalyzes the amidation of bile acids (BAs) with the amino acid taurine. Selective for taurine conjugation of cholyl CoA and only taurine-conjugated BAs are found in bile. Amidation of BAs in the liver with taurine prior to their excretion into bile is an important biochemical event in bile acid metabolism. This conjugation (or amidation) plays several important biological roles in that it promotes the secretion of BAs and cholesterol into bile and increases the detergent properties of BAs in the intestine, which facilitates lipid and vitamin absorption. May also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids. In vitro, catalyzes the hydrolysis of long- and very long-chain saturated acyl-CoAs to the free fatty acid and coenzyme A (CoASH), and conjugates glycine to these acyl-CoAs.
  • 基因功能参考文献：
    1. cytosolic BACAT enzyme may play important roles in protection against toxicity by accumulation of unconjugated bile acids and non-esterified very long-chain fatty acids PMID: 12810727
  • 亚细胞定位：
    Cytoplasm, cytosol. Peroxisome.
  • 蛋白家族：
    C/M/P thioester hydrolase family
  • 组织特异性：
    Highly expressed in liver, kidney, gallbladder, proximal intestine and distal intestine. Weakly expressed in adrenal gland, lung, brain and muscle.
  • 数据库链接：

    KEGG: mmu:12012

    STRING: 10090.ENSMUSP00000041983

    UniGene: Mm.2859