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  4. Recombinant Mouse CXADR-like membrane protein (Clmp), partial

Recombinant Mouse CXADR-like membrane protein (Clmp), partial

  • 中文名称：
    Recombinant Mouse CXADR-like membrane protein(Clmp),partial,Yeast
  • 货号：
    CSB-YP823171MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Mouse CXADR-like membrane protein(Clmp),partial,Yeast
  • 货号：
    CSB-EP823171MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Mouse CXADR-like membrane protein(Clmp),partial,Yeast
  • 货号：
    CSB-EP823171MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Mouse CXADR-like membrane protein(Clmp),partial,Yeast
  • 货号：
    CSB-BP823171MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Mouse CXADR-like membrane protein(Clmp),partial,Yeast
  • 货号：
    CSB-MP823171MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Clmp
  • Uniprot No.：
  • 别名：
    Clmp; Acam; Asam; Asp5CXADR-like membrane protein; Adipocyte adhesion molecule; Adipocyte-specific protein 5; Coxsackie- and adenovirus receptor-like membrane protein; CAR-like membrane protein
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May be involved in the cell-cell adhesion. May play a role in adipocyte differentiation and development of obesity. Is required for normal small intestine development.
  • 基因功能参考文献：
    1. the levels of mRNAs encoding Connexin43 or Connexin45 were not or were only marginally affected, respectively, by Clmp deficiency, the absence of CLMP caused a severe reduction of both proteins in smooth muscle cells of the intestine and of Connexin43 in the ureter. PMID: 29361518
    2. Data (including data from studies in transgenic mice) suggest that, when Acam/Clmp is abundantly expressed on plasma membrane of mature adipocytes, mice are protected from obesity and diabetes with prominent reduction of adipose tissue mass and smaller size of adipocytes; studies used high-fat, high-sucrose diet to induce obesity and diabetes in control mice. PMID: 26956488
    3. We identified ACAM (adipocyte adhesion molecule), a novel homologue of the CTX (cortical thymocyte marker in Xenopus) gene family, which may be the critical adhesion molecule in adipocyte differentiation and development of obesity. PMID: 15563274
    4. Expression of CLMP, a novel tight junction protein, is mediated via the interaction of GATA with the Kruppel family proteins, KLF4 and Sp1, in mouse TM4 Sertoli cells. PMID: 17620326
    5. TNFalpha-mediated mRNA degradation of the CLMP gene is controlled by TTP through the JNK signalling cascade PMID: 18047469

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  • 亚细胞定位：
    Cell junction, tight junction. Cell membrane; Single-pass type I membrane protein.
  • 组织特异性：
    Predominantly expressed in epithelial cells within different tissues and in the white adipose tissue. Expressed at high levels in the heart and brain, at intermediate levels in the lung, skeletal muscle, kidney and testis and at low levels in the liver an
  • 数据库链接：

    KEGG: mmu:71566

    STRING: 10090.ENSMUSP00000034522

    UniGene: Mm.280560