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  4. Recombinant Mouse Calcium/calmodulin-dependent protein kinase II inhibitor 1 (Camk2n1)

Recombinant Mouse Calcium/calmodulin-dependent protein kinase II inhibitor 1 (Camk2n1)

  • 中文名称：
    Recombinant Mouse Calcium/calmodulin-dependent protein kinase II inhibitor 1(Camk2n1)
  • 货号：
    CSB-EP004469MO
  • 规格：
    ￥1836
  • 图片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他：

产品详情

  • 纯度：
    Greater than 90% as determined by SDS-PAGE.
  • 基因名：
    Camk2n1
  • Uniprot No.：
  • 别名：
    Camk2n1Calcium/calmodulin-dependent protein kinase II inhibitor 1; calcium/calmodulin-dependent protein kinase II inhibitor alpha; mCaMKIINalpha
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full Length
  • 来源：
    E.coli
  • 分子量：
    24.5kDa
  • 表达区域：
    1-78aa
  • 氨基酸序列
    MSEVLPYGDEKLSPYGDGGDVGQIFSCRLQDTNNFFGAGQSKRPPKLGQIGRSKRVVIEDDRIDDVLKTMTDKAPPGV
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 6xHis-SUMO-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Tris-based buffer,50% glycerol
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Potent and specific inhibitor of CaM-kinase II (CAMK2).
  • 基因功能参考文献：
    1. Camk2n1 down-regulation caused dorsal striatum-related cognitive disorders by inhibiting synaptic plasticity. PMID: 28890075
    2. The mouse Ca2+/calmodulin kinase II inhibitor alpha (CaMKIINalpha) gene encodes a 2.9kb brain-specific transcript whose expression is downregulated in mouse brain during Japanese encephalitis virus and rabies virus infection. PMID: 17010311
    3. hCaMKIINbeta may play an important role in the regulation of tumor cell growth PMID: 19586909
    4. Camk2n1 mRNA expression is down regulated in mouse brain during virus infection PMID: 17010311
    5. Camk2n1 was shown to be a 37 kDa protein localized in the post synaptic density (PSD) of mouse brain PMID: 17350603

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  • 亚细胞定位：
    Cell junction, synapse, synaptosome. Cell junction, synapse, postsynaptic density.
  • 蛋白家族：
    CAMK2N family
  • 组织特异性：
    Brain specific (at protein level).
  • 数据库链接：

    KEGG: mmu:66259

    STRING: 10090.ENSMUSP00000060349

    UniGene: Mm.41603