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  4. Recombinant Mouse Centrosomal protein of 19 kDa (Cep19)

Recombinant Mouse Centrosomal protein of 19 kDa (Cep19)

  • 中文名称：
    Recombinant Mouse Centrosomal protein of 19 kDa(Cep19),Yeast
  • 货号：
    CSB-YP871876MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Mouse Centrosomal protein of 19 kDa(Cep19),Yeast
  • 货号：
    CSB-EP871876MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Mouse Centrosomal protein of 19 kDa(Cep19),Yeast
  • 货号：
    CSB-EP871876MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Mouse Centrosomal protein of 19 kDa(Cep19),Yeast
  • 货号：
    CSB-BP871876MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Mouse Centrosomal protein of 19 kDa(Cep19),Yeast
  • 货号：
    CSB-MP871876MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Cep19
  • Uniprot No.：
  • 别名：
    Cep19Centrosomal protein of 19 kDa; Cep19
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-163
  • 氨基酸序列
    MKYIAKKCGV RFQPPAVILI YENETEGKSR QRIMPVRNFS KFSDCTRAAE QLKNNPRHKS YLEQVPLKQL EKLFVFLRGS LQGQSLAETM EQIRRETTID PEEDLNKLDD KELAKRKSIM DELFEKNQKR KDDPTFVYDV EVEFPQDEQL LSCSWDTASV DDF
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Required for ciliation. Recruits the RABL2B GTPase to the ciliary base to initiate ciliation. After specifically capturing the activated GTP-bound RABL2B, the CEP19-RABL2B complex binds intraflagellar transport (IFT) complex B from the large pool pre-docked at the base of the cilium and thus triggers its entry into the cilia. Involved in the early steps in cilia formation by recruiting the ciliary vesicles (CVs) to the distal end of the mother centriole where they fuse to initiate cilium assembly. Involved in microtubule (MT) anchoring at centrosomes.
  • 基因功能参考文献：
    1. loss of the ciliary protein CEP19 in humans and mice causes morbid obesity. PMID: 24268657
  • 亚细胞定位：
    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, cilium basal body.
  • 蛋白家族：
    CEP19 family
  • 数据库链接：

    KEGG: mmu:66994

    UniGene: Mm.22990