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  4. Recombinant Mouse Cysteine-rich secretory protein 2 (Crisp2)

Recombinant Mouse Cysteine-rich secretory protein 2 (Crisp2)

  • 中文名称：
    Recombinant Mouse Cysteine-rich secretory protein 2(Crisp2),Yeast
  • 货号：
    CSB-YP005975MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Mouse Cysteine-rich secretory protein 2(Crisp2),Yeast
  • 货号：
    CSB-EP005975MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Mouse Cysteine-rich secretory protein 2(Crisp2),Yeast
  • 货号：
    CSB-EP005975MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Mouse Cysteine-rich secretory protein 2(Crisp2),Yeast
  • 货号：
    CSB-BP005975MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Mouse Cysteine-rich secretory protein 2(Crisp2),Yeast
  • 货号：
    CSB-MP005975MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Crisp2
  • Uniprot No.：
  • 别名：
    Crisp2; Tpx-1; Tpx1Cysteine-rich secretory protein 2; CRISP-2; Testis-specific protein TPX-1
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    23-243
  • 氨基酸序列
    KDPDFTSL LTNQLQVQRE IVNKHNELRR SVNPTGSDIL KMEWSIQATT NAQKWANKCI LEHSSKDDRK INIRCGENLY MSTDPTLWST VIQSWYNENE DFVYGVGAKP NSAVGHYTQL VWYSSFKIGC GIAYCPNQDN LKYFYVCHYC PMGNNVMKKS TPYQQGTPCA SCPNNCENGL CTNSCDFEDL LSNCESLKTS AGCKHELLKT KCQATCLCED KIH
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation.
  • 基因功能参考文献：
    1. Crisp2 genetic defects in sperm from humans and mice result in male infertility. PMID: 26786179
    2. expression and localization of SHTAP in testis and sperm raise the possibility that the SHTAP-CRISP2 complex has a potential role in sperm formation and/or function. PMID: 19686095
    3. Tpx-1 Crisp domain on its own can regulate ion channel activity and provide compelling evidence for a role for Tpx-1 in the regulation of Ca(2+) fluxes observed during sperm capacitation. PMID: 16339766
    4. Evidence for a functional role of CRISP2 in fertilization. PMID: 17202389
    5. These data raise the possibility that CRISP2 is a MAP3K11-modifying protein or, alternatively, that MAP3K11 acts to phosphorylate CRISP2 during acrosome development. PMID: 17377140

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  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    CRISP family
  • 组织特异性：
    Testis.
  • 数据库链接：

    KEGG: mmu:22024

    STRING: 10090.ENSMUSP00000024724

    UniGene: Mm.1296