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  4. Recombinant Mouse Cytochrome P450 2S1 (Cyp2s1)

Recombinant Mouse Cytochrome P450 2S1 (Cyp2s1)

  • 中文名称：
    Recombinant Mouse Cytochrome P450 2S1(Cyp2s1),Yeast
  • 货号：
    CSB-YP884066MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Mouse Cytochrome P450 2S1(Cyp2s1),Yeast
  • 货号：
    CSB-EP884066MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Mouse Cytochrome P450 2S1(Cyp2s1),Yeast
  • 货号：
    CSB-EP884066MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Mouse Cytochrome P450 2S1(Cyp2s1),Yeast
  • 货号：
    CSB-BP884066MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Mouse Cytochrome P450 2S1(Cyp2s1),Yeast
  • 货号：
    CSB-MP884066MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Cyp2s1
  • Uniprot No.：
  • 别名：
    Cyp2s1Cytochrome P450 2S1; EC 1.14.14.-; CYPIIS1; Hydroperoxy icosatetraenoate dehydratase; EC 4.2.1.152; Thromboxane-A synthase; EC 5.3.99.5
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-501
  • 氨基酸序列
    MEAASTWALL LALLLLLLLL SLTLFRTPAR GYLPPGPTPL PLLGNLLQLR PGALYSGLLR LSKKYGPVFT VYLGPWRRVV VLVGHDAVRE ALGGQAEEFS GRGTLATLDK TFDGHGVFFA NGERWKQLRK FTLLALRDLG MGKREGEELI QAEVQSLVEA FQKTEGRPFN PSMLLAQATS NVVCSLVFGI RLPYDDKEFQ AVIQAASGTL LGISSPWGQA YEMFSWLLQP LPGPHTQLQH HLGTLAAFTI QQVQKHQGRF QTSGPARDVV DAFLLKMAQE KQDPGTEFTE KNLLMTVTYL LFAGTMTIGA TIRYALLLLL RYPQVQQRVR EELIQELGPG RAPSLSDRVR LPYTDAVLHE AQRLLALVPM GMPHTITRTT CFRGYTLPKG TEVFPLIGSI LHDPAVFQNP GEFHPGRFLD EDGRLRKHEA FLPYSLGKRV CLGEGLARAE LWLFFTSILQ AFSLETPCPP GDLSLKPAIS GLFNIPPDFQ LRVWPTGDQS R
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    A cytochrome P450 monooxygenase involved in the metabolism of retinoids and eicosanoids. In epidermis, may contribute to the oxidative metabolism of all-trans-retinoic acid. For this activity, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Additionally, displays peroxidase and isomerase activities toward various oxygenated eicosanoids such as prostaglandin H2 (PGH2) and hydroperoxyeicosatetraenoates (HPETEs). Independently of cytochrome P450 reductase, NADPH, and O2, catalyzes the breakdown of PGH2 to hydroxyheptadecatrienoic acid (HHT) and malondialdehyde (MDA), which is known to act as a mediator of DNA damage.
  • 基因功能参考文献：
    1. no Cyp2s1 protein was detected in aortae from wild-type mice it was expressed in aortae and macrophage foam cells from ApoE(-/-) mice PMID: 23224081
    2. identify a novel regulatory cassette that mediates changes in Cyp2s1 expression PMID: 17277313
  • 亚细胞定位：
    Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
  • 蛋白家族：
    Cytochrome P450 family
  • 数据库链接：

    KEGG: mmu:74134

    STRING: 10090.ENSMUSP00000041175

    UniGene: Mm.275188