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  4. Recombinant Mouse Cytosolic Fe-S cluster assembly factor NUBP1 (Nubp1)

Recombinant Mouse Cytosolic Fe-S cluster assembly factor NUBP1 (Nubp1)

  • 中文名称：
    小鼠Nubp1重组蛋白
  • 货号：
    CSB-YP889917MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Nubp1重组蛋白
  • 货号：
    CSB-EP889917MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Nubp1重组蛋白
  • 货号：
    CSB-EP889917MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Nubp1重组蛋白
  • 货号：
    CSB-BP889917MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Nubp1重组蛋白
  • 货号：
    CSB-MP889917MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Nubp1
  • Uniprot No.：
  • 别名：
    Nubp1; Cytosolic Fe-S cluster assembly factor NUBP1; Nucleotide-binding protein 1; NBP 1
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-320
  • 氨基酸序列
    MEEAPHGCPG ADSAQAGRGA SCQGCPNQRL CASGAGAAPD PAVEEIREKM KTVRHKLLVL SGKGGVGKST FSAHLAHGLA EDGDTQVALL DIDICGPSIP KIMGLEGEQV HQSGSGWSPV YVDDNLGVMS VGFLLSSPDD AVIWRGPKKN GMIKQFLRDV DWGDVDYLIV DTPPGTSDEH LSVVQYLAAA HIDGAVILTT PQEVALQDVR KEISFCHKVK LPIIGVVENM SGFICPKCKK ESQIFPPTTG GAEAMCQDLR IPLLGKVPLD PHIGKSCDKG QSFFVEAPDS PATAAYRSII QRIRDFCNSH QSHAETLISP
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Implicated in the regulation of centrosome duplication. Negatively regulates cilium formation and structure.
  • 基因功能参考文献：
    1. KATNAL2 isoforms interact with themselves, with each other and with Nubp1 and Nubp2. PMID: 26153462
    2. The nucleotide-binding proteins Nubp1 and Nubp2 are negative regulators of ciliogenesis. PMID: 23807208
    3. Nubp1 represents an essential protein for lung progenitor survival by coordinating vital cellular processes including cell polarity and centrosomal dynamics PMID: 23028652
    4. The C-terminal domain or motif of Nubp1 plays an important role in regulation of localization of Nubp1 protein. PMID: 19263241
    5. KIFC5A interacts with nucleotide-binding proteins 1 and 2 (Nubp1 and Nubp2). Nubp1 and Nubp2 also interact with each other. PMID: 16638812

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  • 亚细胞定位：
    Cytoplasm. Nucleus. Cell projection. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole.
  • 蛋白家族：
    Mrp/NBP35 ATP-binding proteins family, NUBP1/NBP35 subfamily
  • 组织特异性：
    Expressed in trachea epithelial cells, and kidney inner medullary collecting duct cells.
  • 数据库链接：

    KEGG: mmu:26425

    STRING: 10090.ENSMUSP00000023146

    UniGene: Mm.29037