Recombinant Mouse Cytosolic phospholipase A2 beta (Pla2g4b)
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货号:CSB-YP018098MO
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规格:
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来源:Yeast
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其他:
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货号:CSB-EP018098MO
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规格:
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来源:E.coli
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其他:
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货号:CSB-EP018098MO-B
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规格:
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来源:E.coli
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共轭:Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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其他:
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货号:CSB-BP018098MO
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规格:
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来源:Baculovirus
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其他:
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货号:CSB-MP018098MO
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规格:
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来源:Mammalian cell
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其他:
产品详情
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纯度:>85% (SDS-PAGE)
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基因名:Pla2g4b
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Uniprot No.:
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别名:Pla2g4b; Cytosolic phospholipase A2 beta; cPLA2-beta; EC 3.1.1.4; Phospholipase A2 group IVB
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种属:Mus musculus (Mouse)
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蛋白长度:Full length protein
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表达区域:1-782
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氨基酸序列MQAKVPETCL LTVRVLRASG LPSKDLVTSS DCYVTLNLPT ASSHTLQTRT VKNSRNPVWN QNFHFRIHRQ LKNVMELKVF DHDLVTRDDP VLSVLFDVGT LQIGTQRQSF SLGTQEKGCL EVEFRLQTLT DCEEQLISNG IVVARELSCL HVELKRTGDP KRSERKVQLV VAGACEGPQD ASAGTGSFHF HYPACWEQEL NVHLQDDPHE QLKVPLRTLP SSQLVRLVFP TSQEPLMRLE LKKEEGPKEL AVRLGCGPCP EEQAFLSKRK QVVAAALKKA LQLDQDLHED EIPVIAVMAT GGGIRAMTSL YGQLAGLQEL GLLDCISYIT GASGSTWALA NLYEDPEWSQ KDLAGPTEVL KTQVTKSKLG ALAPSQLWRY RQELAERARL GHPTCFTNLW ALINEALLHD KPHEHKLSDQ REALSRGQNP LPIYCALNSK EQGLSTFDFG EWCEFSPYEV GFPKYGAFIS SELFGSEFFM GRLVKQLPES RICFLEGIWS NLFAASLQDS LYWSSEPSQF WDRWAQDQAN LDKEQVPHLK IAEPPTMAGR IAELFTDLLT KRPLAHATHN FTRGLHFHKD YFQNSHFSAW KASKLDRLPN QLTPTEPHLC LLDVGYLINT SCPPLLQPTR DVDLILSLDY NLYGAFQQLQ LLSRFCQEQG IPFPSISPSP EEQRQPQECH LFCDPAQPEA PAVLHFPLVN DSFQDYSAPG VPRTSEEKAA GEVNLSSSDS PYHYTKVTYS QEDVDKLLRL THYNICNNQD RLREAMHQAV QRRRKRKQFR PE
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蛋白标签:Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially. -
产品提供形式:Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand. -
复溶:We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
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储存条件:Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
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保质期:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. -
货期:Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
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注意事项:Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Datasheet :Please contact us to get it.
靶点详情
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功能:Calcium-dependent phospholipase A1 and A2 and lysophospholipase that may play a role in membrane phospholipid remodeling. Cleaves the ester bond of the fatty acyl group attached to the sn-1 or sn-2 position of phospholipids (phospholipase A1 and A2 activity, respectively), producing lysophospholipids that may be used in deacylation-reacylation cycles. The PLA1 versus PLA2 activity ratio appears to depend on the phospholipid headgroup, with mainly PLA2 activity toward anionic phospholipids such as phosphatidylglycerols. Hydrolyzes with high efficiency lysophospholipids enabling complete deacylation.
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基因功能参考文献:
- TLR2 cooperates with MyD88, PI3K, and Rac1 in lipoteichoic acid-induced cPLA2/COX-2-dependent airway inflammatory responses PMID: 20167866
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亚细胞定位:Cytoplasm, cytosol. Mitochondrion membrane; Peripheral membrane protein. Early endosome membrane; Peripheral membrane protein.
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数据库链接:
KEGG: mmu:211429
STRING: 10090.ENSMUSP00000118458
UniGene: Mm.41467
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