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  4. Recombinant Mouse Embryonal Fyn-associated substrate (Efs)

Recombinant Mouse Embryonal Fyn-associated substrate (Efs)

  • 货号：
    CSB-YP007470MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP007470MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP007470MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP007470MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP007470MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Efs
  • Uniprot No.：
  • 别名：
    Efs; SinEmbryonal Fyn-associated substrate; SRC-interacting protein; Signal-integrating protein
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-560
  • 氨基酸序列
    MAIATSAQLA RALYDNTAES PQELSFRRGD VLRVLQREGA GGLDGWCLCS LHGQQGIVPA NRVKLLPAGP APKPSLCPAS PTQPGSSCPT PERGCEEQEV YVIPPPARPC SASGLPARSC SPSSDSIYKV PRGNGMQLTA SRDVAEVYDV PPNILRAPSS CPYDSPASFS CPVAPVVPQP PREDEAPYDV PLALKPPAEL ERDPEWEGGR EPGPPLYAAP SNLKRASALL NLYEAPEELL ANGESRDADE GIYDVPLLGP EPPSPEPPVA SSSTDLDTVA QLPTRSSPPQ HRPRLPSTES LSRRPLPALP VSEAPAPSPA PSPAPGRKGS IQDRPLPPPP PCLPGYGGLK PEGDPECREV ANDPAGPHNE YEGIPMAEEY DYVHLKGVDT AQGSRPLDKA FPVDPELLER GLAERKEALS PEEPLVLSTG DLQLLHFYAG QCQSHYSALQ AAVAALVAST QANQPPCLFV PHGKRVVVAA HRLVFVGDTL GRLAASAALR AQVGAAGTML AQTLRATVLA VKGAALGYPS DTAVQEMARC VAELAGQALR FTTLLDGLLP
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May serve as an activator of SRC and a downstream effector. Interacts with the SH3 domain of FYN and with CRK, SRC, and YES.
  • 基因功能参考文献：
    1. Sin-deficient mice exhibit exaggerated immune responses characterized by enhanced cytokine secretion and T-cell-dependent antibody production. PMID: 16314525
  • 蛋白家族：
    CAS family
  • 组织特异性：
    Widely expressed. Higher levels found in placenta and embryo. Lower levels found in brain, brainstem, muscle and lung. No expression in liver and intestine.
  • 数据库链接：

    KEGG: mmu:13644

    STRING: 10090.ENSMUSP00000022813

    UniGene: Mm.236438