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  4. Recombinant Mouse Endothelin-converting enzyme-like 1 (Ecel1), partial

Recombinant Mouse Endothelin-converting enzyme-like 1 (Ecel1), partial

In Stock
  • 中文名称：
    小鼠Ecel1重组蛋白
  • 货号：
    CSB-EP878117MO
  • 规格：
    ￥2328
  • 图片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他：

产品详情

  • 纯度：
    Greater than 85% as determined by SDS-PAGE.
  • 基因名：
    Ecel1
  • Uniprot No.：
  • 别名：
    Ecel1; Dine; XceEndothelin-converting enzyme-like 1; EC 3.4.24.-; Damage-induced neuronal endopeptidase; Xce protein
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Partial
  • 来源：
    E.coli
  • 分子量：
    13.7 kDa
  • 表达区域：
    1-61aa
  • 氨基酸序列
    MEAPYSMTAHYDEFQEVKYVSRCGTGGARGTSLPPGFPRGSGRSASGSRSGLPRWNRREVC
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged and C-terminal Myc-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Tris-based buffer,50% glycerol
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    3-7 business days
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May contribute to the degradation of peptide hormones and be involved in the inactivation of neuronal peptides.
  • 基因功能参考文献：
    1. This study demonstrated that the ECEL1/DINE G607S and C760R mutations both lead to motor innervation defects as primary causes in ECEL1-mutated congenital contracture disorders. PMID: 29132416
    2. DINE is expressed in cranial and spinal motor neurons both embryonically and after CNS injury PMID: 27656015
    3. DINE enhances axonal regeneration potential of retinal ganglion cells after optic nerve injury. PMID: 28569783
    4. Using two different DINE mutant mice, study found that DINE functional disruption leads to impaired axonal arborization of motor nerves in limb muscles. PMID: 26951213
    5. The data of this study suggested that DINE is a crucial molecule in distal axonal arborization into muscle to establish neuromuscular junctions. PMID: 20484637

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  • 亚细胞定位：
    Membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    Peptidase M13 family
  • 数据库链接：

    KEGG: mmu:13599

    STRING: 10090.ENSMUSP00000027463

    UniGene: Mm.140765