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  4. Recombinant Mouse Estradiol 17-beta-dehydrogenase 11 (Hsd17b11)

Recombinant Mouse Estradiol 17-beta-dehydrogenase 11 (Hsd17b11)

  • 中文名称：
    小鼠Hsd17b11重组蛋白
  • 货号：
    CSB-YP887649MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Hsd17b11重组蛋白
  • 货号：
    CSB-EP887649MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Hsd17b11重组蛋白
  • 货号：
    CSB-EP887649MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Hsd17b11重组蛋白
  • 货号：
    CSB-BP887649MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Hsd17b11重组蛋白
  • 货号：
    CSB-MP887649MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Hsd17b11
  • Uniprot No.：
  • 别名：
    Hsd17b11; Dhrs8; Pan1bEstradiol 17-beta-dehydrogenase 11; EC 1.1.1.62; 17-beta-hydroxysteroid dehydrogenase 11; 17-beta-HSD 11; 17bHSD11; 17betaHSD11; 17-beta-hydroxysteroid dehydrogenase XI; 17-beta-HSD XI; 17betaHSDXI; Dehydrogenase/reductase SDR family member 8
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    22-298
  • 氨基酸序列
    LVKLFIPKK KKSVAGEIVL ITGAGHGIGR LTAYEFAKLN TKLVLWDINK NGIEETAAKC RKLGAQAHPF VVDCSQREEI YSAAKKVKEE VGDVSILVNN AGVVYTADLF ATQDPQIEKT FEVNVLAHFW TTKAFLPVMM KNNHGHIVTV ASAAGHTVVP FLLAYCSSKF AAVGFHRALT DELAALGRTG VRTSCLCPNF INTGFIKNPS TNLGPTLEPE EVVEHLMHGI LTEKQMIFVP SSIALLTVLE RIVPERFLQV LKHRINVKFD AVVGYKDK
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione.
  • 基因功能参考文献：
    1. data indicate that 17beta-HSD11 localizes both in the endoplasmic reticulum and in lipid droplets, depending on physiologic conditions PMID: 17714510
  • 亚细胞定位：
    Endoplasmic reticulum. Lipid droplet.
  • 蛋白家族：
    Short-chain dehydrogenases/reductases (SDR) family, 17-beta-HSD 3 subfamily
  • 组织特异性：
    Expressed in the liver (at protein level). Also expressed in the intestine and, at much lower levels, in the kidney.
  • 数据库链接：

    KEGG: mmu:114664

    STRING: 10090.ENSMUSP00000031251

    UniGene: Mm.258051