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  4. Recombinant Mouse Fc receptor-like B (Fcrlb)

Recombinant Mouse Fc receptor-like B (Fcrlb)

  • 货号：
    CSB-YP008561MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP008561MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP008561MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP008561MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP008561MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Fcrlb
  • Uniprot No.：
  • 别名：
    Fcrlb; Fcrl2; Fcrlm2; Fcry; Freb2Fc receptor-like B; Fc receptor homolog expressed in B-cells protein 2; FREB-2; Fc receptor-like and mucin-like protein 2; Fc receptor-like protein 2; Fc receptor-related protein Y; FcRY
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    18-427
  • 氨基酸序列
    ATL EKPVLTLHPP WTTIFKGERV TLRCDGYHPL LLELRPISTL WYLGHVLLPS HKKSIEVQAP GVYRCQTRGA PVSDPIHLSV SNDWLILQVP YAAVFEGEPL VMRCRGWYDK VVYKLHYYHD GQAVRYFHSS TNYTVLQARA SDSGHYQCSG TMRIPVESAP MFSSKVAVTV QELFQTPVLR TLSPQEARGR VVLRCETRLH PQKRDTPLQF AFYKYSRPVR RFDWGAEYTV PESEVEELES YWCEAATTSR SVRKRSPWLQ LPGRGPVLDL ASTTAPVAQA AALGPGDKPL SFRKTPVSRS VQSVTSIPNS TFAGLQFPAG HVATAGPHAC APLPASAEQS REALQPKVDL LLREMQLLKG LLSRVVLGLK DPQALHELTE TPETPNSHVT VNPATPETTV MEGRVDS
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 基因功能参考文献：
    1. a negative immunomodulatory function for FCRL2 in the regulation of memory B cells. PMID: 21068405
    2. In FCRLB knock-out mice, B-cell developmemt and in vitro response were normal, but in vivo antibody responses to a T-dependent antigen were elevated. The latter response may be due to a promoter polymorphism in the 129/Sv knock-out strain's Fcgr2b allele. PMID: 20869045
    3. Fcry is upregulated by short-term treatment with BAFF/BLyS, which promotes B cell survival rather than proliferation PMID: 16263223
  • 亚细胞定位：
    Cytoplasm. Endoplasmic reticulum.
  • 组织特异性：
    Expressed at low levels. Expressed in B-lymphocytes. Detected in spleen, lymph node, kidney, lung and brain.
  • 数据库链接：

    KEGG: mmu:435653

    STRING: 10090.ENSMUSP00000091895

    UniGene: Mm.337931