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  4. Recombinant Mouse Fidgetin-like protein 1 (Fignl1)

Recombinant Mouse Fidgetin-like protein 1 (Fignl1)

  • 货号：
    CSB-YP807391MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP807391MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP807391MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP807391MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP807391MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Fignl1
  • Uniprot No.：
  • 别名：
    Fignl1Fidgetin-like protein 1; EC 3.6.4.-
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-683
  • 氨基酸序列
    METSSSMSVE TTRSVQVDEW QKNYCVVTSS ICTPKQKADA YRALLLHIQY AYANSEISQV FATNLFKRYT EKYSAIIDSD NVVTGLNNYA ESIFALAGSR QADSNKWQSG LSIDNVFKMS CVQEMMQAGK KFEESLLEPA DASVVLCKEP TAFEVPQLSV CGGSEDADIL SSSGHDTDKT QAIPGSSLRC SPFQSARLPK ETNTTKTCLT SSTSLGESAT AAFHMTPLFG NTEKDTQSFP KTSTGLNMFL SNLSCVPSGC ENPQERKAFN DSDIIDILSN PTLNKAPSKT EDRGRREDNS LPTFKTAKEQ LWVDQKKKGH QSQHTSKSSN GVMKKSLGAG RSRGIFGKFV PPVSNKQDGS EQHAKKHKSS RAGSAEPAHL TDDCLKNVEP RMVELIMNEI MDHGPPVHWD DIAGVEFAKA TIKEIVVWPM MRPDIFTGLR GPPKGILLFG PPGTGKTLIG KCIASQSGAT FFSISASSLT SKWVGEGEKM VRALFAVARC QQPAVIFIDE IDSLLSQRGD GEHESSRRIK TEFLVQLDGA TTSSEDRILV VGATNRPQEI DEAARRRLVK RLYIPLPEAS ARKQIVGNLM SKEQCCLSDE ETDLVVQQSD GFSGADMTQL CREASLGPIR SLHAADIATI SPDQVRPIAY IDFENAFKTV RPTVSPKDLE LYENWNETFG CGK
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Involved in DNA double-strand break (DBS) repair via homologous recombination (HR). Recruited at DSB sites independently of BRCA2, RAD51 and RAD51 paralogs in a H2AX-dependent manner. May regulate osteoblast proliferation and differentiation. May play a role in the control of male meiosis dynamic.
  • 基因功能参考文献：
    1. Fignl1 as a novel actor in mammal's male meiosis dynamics PMID: 22110678
    2. FIGNL1, a subfamily member of the AAA family of proteins, might play some regulatory role in osteoblast proliferation and differentiation. PMID: 17352653
  • 亚细胞定位：
    Nucleus. Cytoplasm. Cytoplasm, perinuclear region.
  • 蛋白家族：
    AAA ATPase family
  • 组织特异性：
    Expressed at high level in the testis. Detected in pachytene spermatocytes and in metaphase spermatocytes (at protein level).
  • 数据库链接：

    KEGG: mmu:60530

    STRING: 10090.ENSMUSP00000036932

    UniGene: Mm.236114