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  4. Recombinant Mouse Glyoxylate reductase/hydroxypyruvate reductase (Grhpr)

Recombinant Mouse Glyoxylate reductase/hydroxypyruvate reductase (Grhpr)

In Stock Promotion
  • 中文名称：
    小鼠Grhpr重组蛋白
  • 货号：
    CSB-EP009897MO
  • 规格：
    ￥1836
  • 促销：
    促销单品低至599元起
  • 图片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他：

产品详情

  • 纯度：
    Greater than 90% as determined by SDS-PAGE.
  • 基因名：
    Grhpr
  • Uniprot No.：
  • 别名：
    Grhpr; GlxrGlyoxylate reductase/hydroxypyruvate reductase; EC 1.1.1.79; EC 1.1.1.81
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full Length
  • 来源：
    E.coli
  • 分子量：
    51.3kDa
  • 表达区域：
    1-328aa
  • 氨基酸序列
    MKPARLMKVFVTGPLPAEGRAALAQAADCEVEQWNSDDPIPRKDLEQGVVGAHGLLCRLSDRVDKKLLDAAGANLRVISTLSVGVDHLALDEIKKRGIRVGYTPGVLTDATAELAVSLLLTTCRRLPEAIEEVKNGGWSSWSPLWMCGYGLSQSTVGIVGLGRIGQAIARRLKPFGVQRFLYTGRQPRPQEAAEFQAEFVPIAQLAAESDFIVVSCSLTPDTMGLCSKDFFQKMKNTAIFINISRGDVVNQEDLYQALASGQIAAAGLDVTTPEPLPPSHPLLTLKNCVILPHIGSATYKTRNTMSLLAANNLLAGLRGEAMPSELKL
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 6xHis-SUMO-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Tris-based buffer,50% glycerol
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    3-7 business days
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Enzyme with hydroxy-pyruvate reductase, glyoxylate reductase and D-glycerate dehydrogenase enzymatic activities. Reduces hydroxypyruvate to D-glycerate, glyoxylate to glycolate oxidizes D-glycerate to hydroxypyruvate.
  • 基因功能参考文献：
    1. These data suggested that GRHPR might exert its pro-apoptosis function in intestinal epithelial cells. Thus, GRHPR might play an important role in regulating IECs apoptosis, and might be a potential therapeutic target for Crohn's disease. PMID: 26997491
    2. data indicate a species-specific regulation by PPARalpha of GRHPR, a key gene of the glyoxylate cycle PMID: 15840574
  • 蛋白家族：
    D-isomer specific 2-hydroxyacid dehydrogenase family
  • 数据库链接：

    KEGG: mmu:76238

    STRING: 10090.ENSMUSP00000047218

    UniGene: Mm.196574