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  4. Recombinant Mouse Growth hormone-releasing hormone receptor (Ghrhr), partial

Recombinant Mouse Growth hormone-releasing hormone receptor (Ghrhr), partial

  • 中文名称：
    小鼠Ghrhr重组蛋白
  • 货号：
    CSB-YP009413MO1
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Ghrhr重组蛋白
  • 货号：
    CSB-EP009413MO1
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Ghrhr重组蛋白
  • 货号：
    CSB-EP009413MO1-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Ghrhr重组蛋白
  • 货号：
    CSB-BP009413MO1
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Ghrhr重组蛋白
  • 货号：
    CSB-MP009413MO1
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    Ghrhr; Grfr; Growth hormone-releasing hormone receptor; GHRH receptor; Growth hormone-releasing factor receptor; GRF receptor; GRFR
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Receptor for GRF, coupled to G proteins which activate adenylyl cyclase. Stimulates somatotroph cell growth, growth hormone gene transcription and growth hormone secretion.
  • 基因功能参考文献：
    1. Data show that cardiac stem cells (CSCs) isolated from mouse, rat and pig myocardium express growth hormone-releasing hormone receptor (GHRH-R) and agonists of GHRH-R stimulate their proliferation and survival. PMID: 25404316
    2. To ascertain whether (splice variant) SV1 mediates mitogenic effects on nonpituitary tissues, we expressed SV1 in 3T3 mouse fibroblasts and studied the properties of the transfected cells PMID: 11773624
    3. Sleep in mice with nonfunctional growth hormone-releasing hormone receptors PMID: 12388430
    4. GHRH receptor may be associated with carcinogenesis PMID: 12867592
    5. Ghrhr(lit/lit) mice deficient in the GHRH receptor gene are resistant to myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis. PMID: 12960295
    6. analysis of receptors for growth hormone-releasing hormone in human osteosarcomas and Ewing's sarcomas PMID: 16820890

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  • 相关疾病：
    Little (lit) mice exhibits anterior pituitary hypoplasia.
  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 2 family
  • 组织特异性：
    Pituitary gland.
  • 数据库链接：

    KEGG: mmu:14602

    STRING: 10090.ENSMUSP00000068120

    UniGene: Mm.89928