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  4. Recombinant Mouse Homeobox protein unc-4 homolog (Uncx)

Recombinant Mouse Homeobox protein unc-4 homolog (Uncx)

  • 中文名称：
    小鼠Uncx重组蛋白
  • 货号：
    CSB-YP025640MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Uncx重组蛋白
  • 货号：
    CSB-EP025640MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Uncx重组蛋白
  • 货号：
    CSB-EP025640MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Uncx重组蛋白
  • 货号：
    CSB-BP025640MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Uncx重组蛋白
  • 货号：
    CSB-MP025640MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Uncx
  • Uniprot No.：
  • 别名：
    Uncx; Uncx4.1; Homeobox protein unc-4 homolog; Homeobox protein Uncx4.1
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-530
  • 氨基酸序列
    MMDGRLLEHP HAQFGGSLGG VVGFPYPLGH HHVYELAGHQ LQSAAAAAAA ASVPFSIDGL LSGSCAAAAA SVVNPTPLLP AACGVAGESQ PFKLADSGDP DKESPGCKRR RTRTNFTGWQ LEELEKAFNE SHYPDVFMRE ALALRLDLVE SRVQVWFQNR RAKWRKKENT KKGPGRPAHN SHPTTCSGEP MDPEEIARKE LEKMEKKKRK HEKKLLKSQS RHLHSPGGLS LHSAPSSDSD SGGGGLSPEP PEPPPPTAAA KGPGAHGSGI AGSAPVPPGE PPAPGTCDPA FYPSQRSGAG SQPRLGRPAD KDTVPCGPGA AATAGLPKAS PFSVESLLSD SPPRRKATPA NAAATAGLDF TPGLPCAPRT LIGKGHFLLY PITQPLGFLV PQAALKGGAG PELVPKDAPP APPAPPAPPA QASFGTFPGP GGAADPAFAR RSPEVVASPG PPAPASFRDL TAAAAESGAG DCADVGTVCP AASPPPPLET SPGPGPRAPS PPGEPATCGA AEPGAATGPS PPEGEEVDMD
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Transcription factor involved in somitogenesis and neurogenesis. Required for the maintenance and differentiation of particular elements of the axial skeleton. May act upstream of PAX9. Plays a role in controlling the development of connections of hypothalamic neurons to pituitary elements, allowing central neurons to reach the peripheral blood circulation and to deliver hormones for control of peripheral functions.
  • 基因功能参考文献：
    1. Uncx4.1 might play an important role during glutamatergic neuronal differentiation in the mouse midbrain. PMID: 23217170
    2. UNCX acts downstream of neural determination factors to broadly control transcriptional mechanisms used by neural progenitor cells to specify neural phenotypes PMID: 20692344
    3. We examined Lunatic Fringe (Lfng) and Uncx4.1 expression in the presomitic mesoderm (PSM) and somites of Jsr-mutant (CKH-Jsr/+) embryos to elucidate pathogenesis of the Jsr mutation. PMID: 15822856
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Paired homeobox family, Unc-4 subfamily
  • 组织特异性：
    Expressed in the paraxial mesoderm, in the developing kidney and central nervous system. In the somite, it is restricted to the caudal half of the newly formed somite and sclerotome. In the central nervous system, it is detected in the developing spinal c
  • 数据库链接：

    KEGG: mmu:22255

    STRING: 10090.ENSMUSP00000031523

    UniGene: Mm.42190