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  4. Recombinant Mouse Immunoglobulin superfamily containing leucine-rich repeat protein 2 (Islr2), partial

Recombinant Mouse Immunoglobulin superfamily containing leucine-rich repeat protein 2 (Islr2), partial

  • 中文名称：
    小鼠Islr2重组蛋白
  • 货号：
    CSB-YP713054MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Islr2重组蛋白
  • 货号：
    CSB-EP713054MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Islr2重组蛋白
  • 货号：
    CSB-EP713054MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Islr2重组蛋白
  • 货号：
    CSB-BP713054MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Islr2重组蛋白
  • 货号：
    CSB-MP713054MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Islr2
  • Uniprot No.：
  • 别名：
    Islr2; Kiaa1465; LinxImmunoglobulin superfamily containing leucine-rich repeat protein 2; Leucine-rich repeat domain and immunoglobulin domain-containing axon extension protein
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Required for axon extension during neural development.
  • 基因功能参考文献：
    1. we identify a novel role for the LRR receptor Islr2 in ensuring proper axon navigation at the optic chiasm of both zebrafish and mouse. PMID: 26492970
    2. Linx guides the extension of thalamocortical axons in the ventral forebrain. PMID: 24930700
    3. During the embryonic stages, mbu-3 was localized to the central nervous system in the brain and spinal cord. In the early post-natal stages, the gene was evenly expressed in the brain. PMID: 19123979
    4. These findings show that LIGs such as Linx physically interact with Trk receptor tyrosine kinases and modulate their activities to control axonal extension, guidance and branching PMID: 19755105
  • 亚细胞定位：
    Cell membrane; Single-pass membrane protein.
  • 组织特异性：
    At E11.5, expressed in spinal nerves, their roots and the ventral spinal cord. At E12.5, detected in the ventral spinal cord, dorsal root ganglia (DRG), dorsal and ventral roots and sympathetic chain ganglia. At E12.5, expressed in almost all motor neuron
  • 数据库链接：

    KEGG: mmu:320563

    STRING: 10090.ENSMUSP00000130879

    UniGene: Mm.186499