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  4. Recombinant Mouse Inactive serine/threonine-protein kinase PLK5 (Plk5)

Recombinant Mouse Inactive serine/threonine-protein kinase PLK5 (Plk5)

  • 中文名称：
    小鼠Plk5重组蛋白
  • 货号：
    CSB-YP677932MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Plk5重组蛋白
  • 货号：
    CSB-EP677932MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Plk5重组蛋白
  • 货号：
    CSB-EP677932MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Plk5重组蛋白
  • 货号：
    CSB-BP677932MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Plk5重组蛋白
  • 货号：
    CSB-MP677932MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Plk5
  • Uniprot No.：
  • 别名：
    Plk5; Inactive serine/threonine-protein kinase PLK5; Polo-like kinase 5; PLK-5
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-595
  • 氨基酸序列
    MEPRSRRRRS RQLVATFLRD PGSGRVYRRG KLIGKGAFSR CYKLTDMSTS AVFALKVVPR GGAGRLRLRG KVEREIALHS RLRHRNIVAF HAHFADRDHV YMVLEYCSRQ SLAHVLKVRR TLTEPEVRYY LRGLVSGLRY LHQQRIVHRD LKPSNFFLNK NMEVKIGDLG LAARVGPAGR CHRVLCGTPN FQAPEVVSRN GHSCKSDIWA LGCIMYTVLT GTPPFAAAPL SEMYQNIRDG HYLEPTHLSP SARSLIARLL APDPAERPSL DHLLQDDFFS QGFTPERLPP HSCHSPPVFA FPPPLGRLFR KVGQLLLTQC RPPCPFTSKE ASGPGEEGTE PDHMEAGNEE RDPLCTEGRI HLLTLGTPRT GLAGPKGSLA LQLEVATRKL FLCLDAGPMA GQDPPGEQRP VLWAPKWVDY SLKYGFGYQL SDGGSGVLFR DGSHMALRPQ GGHVSYQPDQ GTLWTFTLRD VPSPLRAKLA VLRLFACYMQ RRLREEGTVP MPATPASPDI SLLSFIADSQ AMVMLFSNGT VQVSLKTSQT QLVLSGEDED LLLTLQEPGG PAVGVSYTLD VLRSHGFTLA VHHHLRHGLH LLQSV
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Inactive serine/threonine-protein kinase that plays a role in cell cycle progression and neuronal differentiation.
  • 基因功能参考文献：
    1. Plk5 is mostly expressed in the brain of both mice and humans, and it modulates the formation of neuritic processes upon stimulation of the brain-derived neurotrophic factor (BDNF)/nerve growth factor (NGF)-Ras pathway in neurons. PMID: 21245385
    2. DNA and protein sequence analyses show that Plk5 shares more similarities with Plk2 and Plk3 than with Plk1 and Plk4. PMID: 20100802
  • 亚细胞定位：
    Nucleus, nucleolus. Cytoplasm.
  • 蛋白家族：
    Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily
  • 组织特异性：
    Expressed in the cerebellum, eye and brain cortex (at protein level). Expressed in highly differentiated tissues, such as brain, eyes and ovary. Not detectable in proliferating tissues, such as the colon, spleen and placenta.
  • 数据库链接：

    KEGG: mmu:216166

    STRING: 10090.ENSMUSP00000044400

    UniGene: Mm.17613