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  4. Recombinant Mouse Intraflagellar transport protein 74 homolog (Ift74)

Recombinant Mouse Intraflagellar transport protein 74 homolog (Ift74)

  • 货号：
    CSB-YP805913MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP805913MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP805913MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP805913MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP805913MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Ift74
  • Uniprot No.：
  • 别名：
    Ift74; Ccdc2; Cmg1; Intraflagellar transport protein 74 homolog; Capillary morphogenesis gene 1 protein; CMG-1; Coiled-coil domain-containing protein 2
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-600
  • 氨基酸序列
    MASNHKSSAP RPISRGGIGL TGRPPSGIRP PSGNVRVATA MPPTTARPGS RGGPLGTGGV LSSQIKVADR PVTQQGLSGM KTGMKGPQRQ ILDKSYYLGL LRSKISELTT EINKLQKEIE MYNQENSVYL SYEKRAETLA VEIKDFQGQL ADYNMLVDKL NTNTEMEEVM SDYNMLKAQN DRETQSMDVI FTERQAKEKQ IRSVEEEVEQ EKQAADGIIK NMSPEKQVKY IEMKTTNEKL LQELDTLQQQ LDSLNMKKES LETEIAHSQV KQEAVLLYEK LYELESHRDQ MIAEDKSMGS PMEERERLLK QVKEDNQEIA SMERQLTDIK EKINQFSEEI RQLDMDLEEH QGEMNQKYKE LKKREENMDA FIETFEETKN QELERKAQIE ASIITLLEHC SRNINRMKQI SSITNQELKM MQDDLSFKST EMQKSQTTAR NLTSDSQRLQ LDLQKMELLE SKMTEEQQSL KNKIKQMTAD LETYSDLAAL KSSAEEKKKK LHQERTVLST HRNAFKKIME KLTSDYDTLK RQLQDNETHA QLTNLERKWQ HLEQNNFVMK EFIATKSQES DYQPVIKNVM KQIAEYNKTI MDALHNASRS
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Component of the intraflagellar transport (IFT) complex B: together with IFT81, forms a tubulin-binding module that specifically mediates transport of tubulin within the cilium. Binds beta-tubulin via its basic region. Required for ciliogenesis.
  • 基因功能参考文献：
    1. The CMG-1 serves as a transcriptional regulator of proliferation and adhesion-associated genes in early stage male germ-line cells in the testis. PMID: 20545763
    2. Results identify a cDNA encoding the mouse ortholog of capillary morphogenesis gene (CMG)-1, and suggest that CMG-1 may play a role in the transcriptional regulation of the cyclin D2 gene. PMID: 16705683
    3. Ift74 is most abundantly expressed in tissues rich in highly ciliated cells, such as olfactory sensory neurons, and is predicted to be important to cilia. PMID: 17971504
  • 亚细胞定位：
    Cell projection, cilium. Cytoplasmic vesicle.
  • 蛋白家族：
    IFT74 family
  • 数据库链接：

    KEGG: mmu:67694

    STRING: 10090.ENSMUSP00000030311

    UniGene: Mm.240619