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  4. Recombinant Mouse Kinesin-like protein KIF3C (Kif3c)

Recombinant Mouse Kinesin-like protein KIF3C (Kif3c)

  • 货号：
    CSB-YP012337MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP012337MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP012337MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP012337MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP012337MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Kif3c
  • Uniprot No.：
  • 别名：
    Kif3c; Kinesin-like protein KIF3C
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-796
  • 氨基酸序列
    MASKTKASEA LKVVARCRPL SRKEEAAGHE QILTMDVKLG QVTLRNPRAA PGELPKTFTF DAVYDASSKQ ADLYDETVRP LIDSVLQGFN GTVFAYGQTG TGKTYTMQGT WVEPELRGVI PNAFEHIFTH ISRSQNQQYL VRASYLEIYQ EEIRDLLSKE PGKRLELKEN PETGVYIKDL SSFVTKNVKE IEHVMNLGNQ ARAVGSTHMN EVSSRSHAIF VITVECSERG SDGQDHIRVG KLNLVDLAGS ERQNKAGPNA AGGPATQPTA GGGSGSGSAS GSASSGERPK EASKINLSLS ALGNVIAALA GNRSTHIPYR DSKLTRLLQD SLGGNAKTIM VATLGPASHS YDESLSTLRF ANRAKNIKNK PRVNEDPKDT LLREFQEEIA RLKAQLEKKG MLGKRPRRKS SRRKKAVSAP AGYPEGSVIE AWVAEEEDDN NNNHHPPQPI LEAALEKNME NYLQDQKERL EEEKAAIQDD RSLVSEEKQK LLEEKEKMLE DLRREQQATE LLAAKYKAME SKLLIGGRNI MDHTNEQQKM LELKRQEIAE QKRREREMQQ EMLLRDEETM ELRGTYSSLQ QEVEVKTKKL KKLYAKLQAV KAEIQDQHEE YIRVRQDLEE AQNEQTRELK LKYLIIENFI PPEEKNKIMN RLFLDCEEEQ WRFQPLVPAG VNNSQMKKRP TSAVGYKRPI SQYARVAMAM GSHPRYRAEN IMFLELDVSP PAIFEMEFSH DQEQDPRVLH MERLMRLDSF LERPSTTKVR KSRSWCQSPQ RMPPPSTAHA SMTSVPLHPA TVVDHD
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Microtubule-based anterograde translocator for membranous organelles.
  • 基因功能参考文献：
    1. Results reveal that engineered homodimeric KIF3CC is targeted to the microtubule plus-end, acts as a potent catastrophe factor through an increase in microtubule catastrophe frequency, and does so by elimination of the dependence of the catastrophe rate on microtubule lifetime. Moreover, KIF3CC accelerates the catastrophe rate without altering the microtubule growth rate. PMID: 29045878
    2. KIF3C is an injury-specific kinesin that contributes to axon growth and regeneration by regulating and organizing the microtubule cytoskeleton in the growth cone. PMID: 23843507
  • 亚细胞定位：
    Cytoplasm, cytoskeleton.
  • 蛋白家族：
    TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family, Kinesin II subfamily
  • 数据库链接：

    KEGG: mmu:16570

    STRING: 10090.ENSMUSP00000020999

    UniGene: Mm.415417