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  4. Recombinant Mouse Krueppel-like factor 17 (Klf17)

Recombinant Mouse Krueppel-like factor 17 (Klf17)

  • 货号：
    CSB-YP806527MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP806527MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP806527MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP806527MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP806527MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Klf17
  • Uniprot No.：
  • 别名：
    Klf17; Gzf; Zfp393; Znf393Krueppel-like factor 17; Germ cell-specific zinc finger protein; Zinc finger protein 393
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-341
  • 氨基酸序列
    MEQDNKEQAM HQPPMDNKML VPVSNVPVSS GNSGFHQPPA TQYLPEMMRS YMASAEELRC NEREWESQLI RSLPEHGVRC PSQLAPIPFQ NYCQRSIGRG SHVMPVGSSG TLGVTISFSE NLMPQGGLPS SRGVSVMAHS SAPAMPYPMP PTVPATTGSL KHGILLVPGM ASAGTHAVAP FMDQMLHSIN PCNPEMLPAR FQQLLPLDSQ DSLVTESNTQ EEPFVREPPT PAPEGAESPS TSRGATRRQS PVSRPYVCTY NSCGKSYTKR SHLVSHQRKH TGVKPFACDW NGCTWKFFRS DELGRHKRIH TRYRPHKCDE CDREFMRSDH LRQHKRTHLP K
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development.
  • 基因功能参考文献：
    1. ZFP393 functions as a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development PMID: 12351194
    2. demonstrate that KLF17 expression is significantly downregulated in primary human breast cancer samples and that the combined expression pattern of KLF17 and Id1 can serve as a potential biomarker for lymph node metastasis in breast cancer PMID: 19801974
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Sp1 C2H2-type zinc-finger protein family
  • 组织特异性：
    Exclusively expressed in testis and ovary. Localized to step 3-8 spermatids in testis and growing oocytes in ovary.
  • 数据库链接：

    KEGG: mmu:75753

    STRING: 10090.ENSMUSP00000052316

    UniGene: Mm.3848