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  4. Recombinant Mouse Lethal (3)malignant brain tumor-like protein 2 (L3mbtl2)

Recombinant Mouse Lethal (3)malignant brain tumor-like protein 2 (L3mbtl2)

  • 中文名称：
    小鼠L3mbtl2重组蛋白
  • 货号：
    CSB-YP012711MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠L3mbtl2重组蛋白
  • 货号：
    CSB-EP012711MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠L3mbtl2重组蛋白
  • 货号：
    CSB-EP012711MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠L3mbtl2重组蛋白
  • 货号：
    CSB-BP012711MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠L3mbtl2重组蛋白
  • 货号：
    CSB-MP012711MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    L3mbtl2
  • Uniprot No.：
  • 别名：
    L3mbtl2Lethal(3)malignant brain tumor-like protein 2; L(3)mbt-like protein 2
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-703
  • 氨基酸序列
    MEKPRGTEEA PSSEPMEEEE EDDLDLFGGY DSFRSYNSSA GSESSSYLEE SSEAENEDRE AGELPTSPLH LFSSANNRSL DGSGSEPAVC EMCGIVGTRE AFFSKTKRFC SVSCSRSYSS NSKKASILAR LQGKPPTKKA KVLHKAAWSA KIGAFLHAQG TGQLADGTPT GQDALVLGFD WGKFLKDHSY KAAPVSCFKH VPLYDQWEDV MKGMKVEVLN SDAVLPSRVY WIATVIQAAG YRVLLRYEGF ENDASHDFWC NLGTVDVHPI GWCAINSKIL VPPRTIHAKF TDWKSYLMKR LVGSRTLPAD FHIKMVESMK YPFRQGMRLE VVDKTQVSRT RMAVVDTVIG GRLRLLYEDG DSDDDFWCHM WSPLIHPVGW SRRVGHGIKM SDRRCDMSHH PTFRKIYCDA VPYLFKKVRA VYTEGGWFEE GMKLEAIDPL NLGSICVATI CKVLLDGYLM ICVDGGPSTD GSDWFCYHAS SHAIFPATFC QKNDIELTPP KGYETQPFAW ETYLEKTKSK AAPARLFNMD CPNHGFKVGM KLEAVDLMEP RLICVATVKR VVHRLLSIHF DGWDNEYDQW VDCESPDIYP VGWCELTGYQ LQPPVSAEPN TPQKGKDTTK KKKKQFGKKR KRIPSAKTRP LRQGSKKPLL EDNLEALGVS EPVPDDIIAV CVKEEHQDIS SLDRSPSPQL PLPIESIKQE RNN
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'.
  • 基因功能参考文献：
    1. that PRC1 complex participates in the establishment of pluripotency and identify BMP4 signaling as a modulator of PRC1.1 function PMID: 29166607
    2. Disruption of L3mbtl2 results in embryonic lethality with failure of gastrulation. PMID: 22770845
  • 亚细胞定位：
    Nucleus.
  • 组织特异性：
    Ubiquitous.
  • 数据库链接：

    KEGG: mmu:214669

    STRING: 10090.ENSMUSP00000023029

    UniGene: Mm.280768