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  4. Recombinant Mouse Metastasis-associated protein MTA2 (Mta2)

Recombinant Mouse Metastasis-associated protein MTA2 (Mta2)

  • 中文名称：
    小鼠Mta2重组蛋白
  • 货号：
    CSB-YP865639MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Mta2重组蛋白
  • 货号：
    CSB-EP865639MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Mta2重组蛋白
  • 货号：
    CSB-EP865639MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Mta2重组蛋白
  • 货号：
    CSB-BP865639MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Mta2重组蛋白
  • 货号：
    CSB-MP865639MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Mta2
  • Uniprot No.：
  • 别名：
    Mta2; Mta1l1; Metastasis-associated protein MTA2; Metastasis-associated 1-like 1
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-668
  • 氨基酸序列
    MAANMYRVGD YVYFENSSSN PYLVRRIEEL NKTANGNVEA KVVCLFRRRD ISSSLNSLAD SNAREFEEES KQPGVSEQQR HQLKHRELFL SRQFESLPAT HIRGKCSVTL LNETDILNQY LDKEDCFFYS LVFDPVQKTL LADQGEIRVG CKFQAEIPDR LAEGESDNRN QQKMEMKVWD PDNPLTDRQI DQFLVVARAV GTFARALDCS SSIRQPSLHM SAAAASRDIT LFHAMDTLQR NGYDLAKAMS TLVPQGGPVL CRDEMEEWSA SEAMLFEEAL EKYGKDFNDI RQDFLPWKSL ASIVQFYYMW KTTDRYIQQK RLKAAEADSK LKQVYIPTYT KPNPNQIISV GSKPGMNGAG FQKGLTCESC HTTQSAQWYA WGPPNMQCRL CASCWIYWKK YGGLKTPTQL EGAARGTTEP HSRGHLSRPE AQSLSPYTTS ANRAKLLAKN RQTFLLQTTK LTRLARRMCR DLLQPRRAAR RPYAPINANA IKAECSIRLP KAAKTPLKIH PLVRLPLATI VKDLVAQAPL KPKTPRGTKT PINRNQLTQN RGLGGIMVKR SYETMAGAGV PFSANGRPLA SGIRSSSQPA AKRQKLNPAD APNPVVFVAT KDTRALRKAL THLEMRRAAR RPNLPLKVKP TLMTVRPPVP LPASSHPAST NEPIVLED
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May be involved in the regulation of gene expression as repressor and activator. The repression might be related to covalent modification of histone proteins.
  • 基因功能参考文献：
    1. Mta2 expression is up-regulated during testicular Sertoli cells phagocytosis. PMID: 24583130
    2. Sertoli cell-specific expression of MTA2 is required for transcriptional regulation of FSHR gene during spermatogenesis. PMID: 23086931
    3. investigation of expression/role of Mta2 in zygote/blastocyst development: Mta2 appears to be only Mta expressed in zygotes; Mta2 appears to control transcription/expression of H19 and Peg3 in blastocysts; Mta2 may be involved in genetic imprinting PMID: 20720167
    4. results suggest that GATA-3 interacts with MTA-2 to co-ordinately regulate Th2 cytokine and ifng loci during T helper cell differentiation. PMID: 20636338
    5. Assignment of the metastasis-associated gene (Mta1) to mouse chromosome band 12F and the metastasis-associated gene 2 (Mta2) to mouse chromosome band 19B by fluorescence in situ hybridization PMID: 11856890
    6. These results demonstrate the importance of FOG-2/MTA/RbAp interactions for FOG-2-mediated transcriptional repression and further define the molecular interactions between the FOG repression motif and the NuRD complex. PMID: 18067919
    7. Mta2/NuRD is involved in modulating IL-4 and IFN-gamma expression in T cell immune responses PMID: 18353770

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  • 亚细胞定位：
    Nucleus.
  • 数据库链接：

    KEGG: mmu:23942

    STRING: 10090.ENSMUSP00000093959

    UniGene: Mm.25339