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  4. Recombinant Mouse Neuropeptide S (Nps)

Recombinant Mouse Neuropeptide S (Nps)

  • 中文名称：
    小鼠Nps重组蛋白
  • 货号：
    CSB-YP016026MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Nps重组蛋白
  • 货号：
    CSB-EP016026MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Nps重组蛋白
  • 货号：
    CSB-EP016026MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Nps重组蛋白
  • 货号：
    CSB-BP016026MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Nps重组蛋白
  • 货号：
    CSB-MP016026MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Nps
  • Uniprot No.：
  • 别名：
    Nps; Neuropeptide S
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Cytoplasmic domain
  • 表达区域：
    70-89
  • 氨基酸序列
    S FRNGVGSGAK KTSFRRAKQ
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May play an important anorexigenic role. Modulates arousal and anxiety as well as increases locomotor activity. Binds to its receptor NPSR1 with nanomolar affinity to increase intracellular calcium concentrations.
  • 基因功能参考文献：
    1. Study showed that the actions of neuropeptide S influenced the excitability of dorsal raphe and laterodorsal tegmentum neurons, which could play a role in the anxiolytic and arousal-promoting effects of this peptide. PMID: 28655610
    2. NPS-/- mice display significant deficits in exploratory activity, long-term memory and arousal. PMID: 28548278
    3. these results indicate that NPS-NPSR system may regulate locomotion together with the CRF1 system in SN. PMID: 26239581
    4. These data provide evidence for a direct interaction between the corticotropin-releasing factor and the NPS system and thereby extend previous observations of NPS-modulated stress responsiveness towards a mechanistic level. PMID: 22570383
    5. Neuropeptide S knock-out mice display deficits in inhibitory avoidance memory indicating involvement in central noradrenergic systems. PMID: 21150909
    6. Results describe the neuroanatomical, molecular, and functional aspects of neuropeptide S-producing neurons in the mouse brain. PMID: 21452230
    7. These data demonstrate that the distribution pattern of the central neuropeptide S system is only partially conserved between mice and rats. PMID: 21452235
    8. results demonstrate that neuropeptide S and NPSR1 regulate respiratory function through a central nervous system-mediated pathway PMID: 21167892
    9. Data suggest that lithium evokes antagonistic effects on the mediation of hyperlocomotion and protection against lipid peroxidation induced by neuropeptide S. PMID: 19616051
    10. analysis of a neuropeptide S responsive circuitry shaping amygdala activity via the endopiriform nucleus PMID: 18628994
    11. NPS facilitates spatial memory and mitigates MK801-induced spatial memory impairment in mice. PMID: 19429110

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  • 亚细胞定位：
    Secreted.
  • 数据库链接：

    KEGG: mmu:100043254

    STRING: 10090.ENSMUSP00000095597

    UniGene: Mm.192092