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  4. Recombinant Mouse Nuclear protein MDM1 (Mdm1)

Recombinant Mouse Nuclear protein MDM1 (Mdm1)

  • 中文名称：
    小鼠Mdm1重组蛋白
  • 货号：
    CSB-YP883958MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Mdm1重组蛋白
  • 货号：
    CSB-EP883958MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Mdm1重组蛋白
  • 货号：
    CSB-EP883958MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Mdm1重组蛋白
  • 货号：
    CSB-BP883958MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Mdm1重组蛋白
  • 货号：
    CSB-MP883958MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Mdm1
  • Uniprot No.：
  • 别名：
    Mdm1; Mdm-1; Nuclear protein MDM1; Mdm4 transformed 3T3 cell double minute 1 protein; Mouse double minute 1
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-708
  • 氨基酸序列
    MPVRFKGLSE YQRNFLWKKS YLSESYNPSV GQKYSWAGLR SDQLGITKEP GFISKRRVPY HDPQISKYLE WNGTVRKKDT LVPPEPQAFG TPKPQEAEQG EDANQEAVLS LEASRVPKRT RSHSADSRAE GVSDTVEKHQ GVTRSHAPVS ADVELRPSSK QPLSQSIDPR LDRHLRKKAG LAVVPTNNAL RNSEYQRQFV WKTSKESAPV FASNQVFRNK SQIIPQFQGN TFTHETEYKR NFKGLTPVKE PKSREYLKGN SSLEMLTPVK KADEPLDLEV DMASEDSDQS VKKPASWRHQ RLGKVNSEYR AKFLSPAQYF YKAGAWTRVK ENLSNQVKEL REKAESYRKR VQGTHFSRDH LNQIMSDSNC CWDVSSVTSS EGTVSSNIRA LDLAGDLTNH RTPQKHPPTK LEERKVASGE QPLKNSTRRL EMPEPAASVR RKLAWDAEES TKEDTQEEPR AEEDGREERG QDKQTCAVEL EKPDTQTPKA DRLTEGSETS SVSSGKGGRL PTPRLRELGI QRTHHDLTTP AVGGAVLVSP SKVKPPGLEQ RRRASSQDGL ETLKKDITKK GKPRPMSLLT SPAAGMKTVD PLPLREDCEA NVLRFADTLP VSKILDRQPS TPGQLPPCAP PYCHPSSRIQ GRLRDPEFQH NMGKPRTNNL QLHPHDAFND EDADRLSEIS ARSAVSSLRA FQTLARAQKR KENFWGKP
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Microtubule-binding protein that negatively regulates centriole duplication. Binds to and stabilizes microtubules.
  • 基因功能参考文献：
    1. Age-related retinal degeneration in mutants may be the result of depletion of the Mdm1 gene transcript. PMID: 18805803
    2. Depletion of the Mdm1 transcript may underlie the mechanism leading to late-onset progressive retinal degeneration in arrd2 mice. PMID: 18805803
  • 亚细胞定位：
    Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole.
  • 蛋白家族：
    MDM1 family
  • 组织特异性：
    Widely expressed. Expressed at high levels in the testis.
  • 数据库链接：

    KEGG: mmu:17245

    STRING: 10090.ENSMUSP00000127919

    UniGene: Mm.101191