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  4. Recombinant Mouse Nucleolar complex protein 2 homolog (Noc2l)

Recombinant Mouse Nucleolar complex protein 2 homolog (Noc2l)

  • 中文名称：
    小鼠Noc2l重组蛋白
  • 货号：
    CSB-YP894375MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Noc2l重组蛋白
  • 货号：
    CSB-EP894375MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Noc2l重组蛋白
  • 货号：
    CSB-EP894375MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Noc2l重组蛋白
  • 货号：
    CSB-BP894375MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Noc2l重组蛋白
  • 货号：
    CSB-MP894375MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Noc2l
  • Uniprot No.：
  • 别名：
    Noc2l; Nir; Nucleolar complex protein 2 homolog; Protein NOC2 homolog; NOC2-like protein; Novel INHAT repressor
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-747
  • 氨基酸序列
    MAASRAPRRR LEDLSVDEFL ASGFESGSES ELEGAAEERR ARGAAWNRER RGARTSPGPA GRLRKGRASE HKDQLSRLKD RDPEFYKFLQ ENDRSLLDFS DSDSSAEEEE PFHSLPDTLE EASETEEDGG EDSDALPRGL RSKKNEPVPV TLAMVERWRQ GSRHHLTPRL FHEVVQAFRA AVATTQGEQE AAETCRFQVA DSAVFNALVT FCIRDLCGCL QKLLFGKTPK DSNRLLLPSS SPLWGKLRVD VKSYLSAVVQ LAACLAEATV SAAVLQHISS LVPYFLTFPK QCRMLLKRMV VLWSTGEESL RVLAFLVLIR VCRHKKEAFL GPILKQMYIM YVRNCKFTSP STLPLISFMQ RTLTEMLALD PSVSYQHAFL YIRQLAVHLR NAMTTGKKET HQSVYNWQYV HCLYLWCRVL STLGSSEILQ PLLYPLSQII IGCIKLLPTA RFYPLRMHCV RALTLLSQTI GTFIPVLPFI LEIFQQVDFN RRPGRMSSKP INFSVILKLS STNLQEKAYR DGLLEQLCDL ILEYLHSQAH SIAFPELVLP TVLQLKSFLR ECKVANYCRQ VRQLLEKVQE NARHIESLRQ SATFSVSDRT AVDAWEKQVR EEGTPLTRYY GHWKKLRDRE IQLEISGKER LEDLNFPEIK RRKVEDRKDE DRKELKDLFE LDSSEGEDST DFFERGVPRL PEAHQGLKED QEEEDKEEGD SDSEDGDTDT GVDLSELWQL AQGAQDELED LQLSEED
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Acts as an inhibitor of histone acetyltransferase activity; prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner. Acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter. Involved in the regulation of p53/TP53-dependent apoptosis.
  • 亚细胞定位：
    Nucleus, nucleoplasm. Nucleus, nucleolus.
  • 蛋白家族：
    NOC2 family
  • 组织特异性：
    Ubiquitous.
  • 数据库链接：

    STRING: 10090.ENSMUSP00000137253

    UniGene: Mm.423051