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  4. Recombinant Mouse Opticin (Optc)

Recombinant Mouse Opticin (Optc)

  • 货号：
    CSB-YP016362MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP016362MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP016362MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP016362MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP016362MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Optc
  • Uniprot No.：
  • 别名：
    Optc; Opt; Opticin; Oculoglycan
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    20-328
  • 氨基酸序列
    A SLLGEREREE QSPEEGDTYA SLYVGNHTLS IEDYNEVIDL SNYEELADYG DQIPEAKISN LTLPTRTSPT STVAQKTLSP NLTMAVPTTT GLLNSQSSHG LPTCLVCVCL GSSVYCDDAD LENIPPLPQM TTYLYARFNH ISHIQAGDFK GLTKLRRIDL SGNSISSIHN DALRLLPALQ DLILPENQLA ALPVLPSGIE FLDVRLNRLQ SSGIQPEAFV ALKKLQFLYL ANNMLDSIPG PLPLSLRSLH LQNNMIETME SDTFCDTGEH RHERRQLEDI RLDGNPINLS LFPEAYFCLP RLPVGHFT
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Inhibits angiogenesis in the vitreous humor of the eye, and therefore represses neovascularization. Binds collagen fibrils. May be involved in collagen fiber organization via regulation of other members of the small leucine-rich repeat proteoglycan superfamily.
  • 基因功能参考文献：
    1. opticin binds to collagen and thereby competitively inhibits endothelial cell interactions with collagen via alpha(1)beta(1) and alpha(2)beta(1) integrins, thereby preventing the strong adhesion that is required for proangiogenic signaling via these integrins. PMID: 22669977
  • 亚细胞定位：
    Secreted, extracellular space, extracellular matrix.
  • 蛋白家族：
    Small leucine-rich proteoglycan (SLRP) family, SLRP class III subfamily
  • 组织特异性：
    Expressed in cartilage (at protein level). Expressed in the vitreous collagen, inner limiting membrane, lens capsule, trabecular meshwork, anterior surface of the iris, the area adjacent to the nonpigmented ciliary epithelium, and weakly expressed in the
  • 数据库链接：

    KEGG: mmu:269120

    STRING: 10090.ENSMUSP00000120568

    UniGene: Mm.59985