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  4. Recombinant Mouse PCNA-interacting partner (Parpbp)

Recombinant Mouse PCNA-interacting partner (Parpbp)

  • 中文名称：
    小鼠Parpbp重组蛋白
  • 货号：
    CSB-YP760822MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Parpbp重组蛋白
  • 货号：
    CSB-EP760822MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Parpbp重组蛋白
  • 货号：
    CSB-EP760822MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Parpbp重组蛋白
  • 货号：
    CSB-BP760822MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Parpbp重组蛋白
  • 货号：
    CSB-MP760822MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Parpbp
  • Uniprot No.：
  • 别名：
    Parpbp; Pari; PCNA-interacting partner; PARI; PARP-1 binding protein; PARP1-binding protein; PARPBP
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-573
  • 氨基酸序列
    MAVLNQLPVL GMIKEFRRSW RALCSSERTT LCGPDSMLLA LQLSMAENNK QHRGEFTVCL SDVLLTWKYF LHEKLNLPIE NMKVVEHYED IKKTYDDFLK NSNTLDLIDV YKKCSSLTSN YENNMISPIQ LRDFLSGTEY AVSDEANPHM PESPVKCSQN DEQVRVLVKK IFFSYLSLLV NSKNDLALAS ILNIPDRGLG REAFTNLKHA AREKQLSMFL MATSFIRTLE LGGKGYAPSP SDPLWAHVKG LSEFINFIDK LDEILGKIPN PSLAGSRILS AIKMQLIKGH SSGEPFYKAV EEVVQDLNLR IKNIINSQEG VAVSANNISP VPPKSFAINH DTAYCGRDAV KILLVLLDED AASAPTRNKA ELLYNDESTV PHSGPSVLTL FRSPTQEKNT SVKPLRERIH KSLQTEKNKM WQTLIRSQFA CTYKDDCIMS KNKWHVNSSS KPLSALHLED DVSEGAQSSV GKARIEASSE NAHVGRWKGD KLPRKSTQRQ ISKGKQLDLD SENLHCDRGN ELYQHKNIKI PKVPSGSHSK AGGKLAQGTK GNRCPARGKL IPGQTKLTQF FML
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Required to suppress inappropriate homologous recombination, thereby playing a central role DNA repair and in the maintenance of genomic stability. Antagonizes homologous recombination by interfering with the formation of the RAD51-DNA homologous recombination structure. Binds single-strand DNA and poly(A) homopolymers. Positively regulate the poly(ADP-ribosyl)ation activity of PARP1; however such function may be indirect.
  • 基因功能参考文献：
    1. PARI is a latent modulator of stalled fork processing, which is required for stable genome inheritance under both endogenous and exogenous replication stress PMID: 28894029
    2. Parpbp(4930547N16Rik) is strongly co-expressed with known cancer-associated genes. PMID: 23039964
  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    PARI family
  • 组织特异性：
    Expressed in the ovary, Sertoli cells of the testis and in granular cells within the cerebellum.
  • 数据库链接：

    KEGG: mmu:75317

    STRING: 10090.ENSMUSP00000038375

    UniGene: Mm.179378