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  4. Recombinant Mouse Peptidyl-prolyl cis-trans isomerase FKBP7 (Fkbp7)

Recombinant Mouse Peptidyl-prolyl cis-trans isomerase FKBP7 (Fkbp7)

  • 货号：
    CSB-YP008703MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP008703MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP008703MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP008703MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP008703MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    Fkbp7; Fkbp23; Peptidyl-prolyl cis-trans isomerase FKBP7; PPIase FKBP7; EC 5.2.1.8; 23 kDa FK506-binding protein; 23 kDa FKBP; FKBP-23; FK506-binding protein 7; FKBP-7; Rotamase
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    20-218
  • 氨基酸序列
    Q GQTKEESTEE VKIEVLHRPE NCSKTSRKGD LLNAHYDGYL AKDGSKFYCS RTQDEGHPKW FVLGVGHVIK GLDIAMMDMC PGEKRKVIIP PSFAYGKEGY AEGKIPPNAT LMFEIELYAV TKGPRSIETF KQIDTDNDRQ LSKAEIELYL QKDFEKDANP RDKSYQKAVL EDIFKKNDHN GDGFISPKEY NVHQHDEL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    PPIases accelerate the folding of proteins during protein synthesis.
  • 基因功能参考文献：
    1. FKBP23 is demonstrated to mediate functions of BiP by catalyzing the Pro(117)cis/trans conformational interconversion in the ATPase domain of BiP. PMID: 21527244
    2. mFKBP23 binds to immunoglobulin binding protein (mBiP,Hsp70); the binding of the C-terminus is Ca(2+)-dependent and the switch point is between 2 and 3 mM, no binding being detected at high concentration of calcium PMID: 14960307
    3. In this study, we demonstrate the ability of mFKBP23 to modulate the ATPase activity of BiP, and that the bound mFKBP23, but not the free mFKBP23, can suppress the ATPase activity of mBiP through its PPIase activity. PMID: 17223077
    4. binds to Grp78 (Bip) in endoplasmic reticulum. PMID: 17425118
  • 亚细胞定位：
    Endoplasmic reticulum lumen.
  • 组织特异性：
    Expressed at highest levels in heart, lung and testis. Weakly expressed in kidney and lymph node. Little or no expression detected in brain, thymus, spleen and liver.
  • 数据库链接：

    KEGG: mmu:14231

    STRING: 10090.ENSMUSP00000002809

    UniGene: Mm.24720