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  4. Recombinant Mouse Prolyl endopeptidase-like (Prepl)

Recombinant Mouse Prolyl endopeptidase-like (Prepl)

  • 货号：
    CSB-YP018665MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP018665MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP018665MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP018665MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP018665MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Prepl
  • Uniprot No.：
  • 别名：
    Prepl; Kiaa0436; Prolyl endopeptidase-like; EC 3.4.21.-; Prolylendopeptidase-like
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-725
  • 氨基酸序列
    MLQTAKFSLR ALKHSIPHLG NCMQKQSYRN VAGPYYSRVR LKKYHLTKCL QNKPRIAGLA RNIPSRSFSC KDLLPIKPES EKPISENMDA FEKVRTRLET QPQEEYEVVN AEIKHGGFVY YQEGCCLVRS KDEEADSDNY EVLFNLEELK LDQPFIDCIR VAPDEKYVAA KIRTEDSETS TLVVVKLSDQ PVMEASFPNV SSFEWVKDEE DEDVLFYTFQ RNLRCHDVYR ATFGDNKRNE RFYTEKDPSY FVFLYLTKDS RFLTLNIMNK TTSEVWLIDG LSPWDPPVLI QKRIHGMLYY VEHRDDELYI LTNVGEPTEF KLMRTAADAP AIMNWDLFFT MKRNTKVVDL DMFKDHCVLF LKHSNLLYVN VIGLADDSVR SLKLPPWACG FIMDTNSDPK NCPFQLCSPI RPPKYYTYKF AEGKLFEETG HEDPITKTSR VLRIEAKSKD GKLVPMTVFH KTDSEDLQRK PLLVHVYGAY GMDLKMNFRP EKRVLVDDGW ILAYCHVRGG GELGLQWHAD GRLTKKLNGL ADLVACIKTL HSQGFSQPSL TTLSAFSAGG VLVGALCNSK PELLRAVTLE APFLDVLNTM LDTTLPLTLE ELEEWGNPSS DEKHKNYIKR YCPCQNIKPQ HYPSVHITAY ENDERVPLKG IVNYTEKLKE AVAEHTKGAG EGYQPPNIIL DIQPGGNHVI EDSHKKITTQ MKFLYEELGL DSTDAFEALK KYLKF
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Serine peptidase whose precise substrate specificity remains unclear. Does not cleave peptides after a arginine or lysine residue. Regulates trans-Golgi network morphology and sorting by regulating the membrane binding of the AP-1 complex. May play a role in the regulation of synaptic vesicle exocytosis.
  • 基因功能参考文献：
    1. The data demonstrate PREPL as an AP-1 effector that takes part in the regulation of AP-1 membrane binding. PREPL is highly expressed in brain and at lower levels in muscle and kidney. PMID: 23321636
  • 亚细胞定位：
    Cytoplasm, cytosol. Golgi apparatus, trans-Golgi network. Cytoplasm, cytoskeleton. Golgi apparatus. Nucleus.
  • 蛋白家族：
    Peptidase S9A family
  • 组织特异性：
    Highly expressed in the brain, specifically in neurons of the neocortex, substantia nigra, locus coeruleus, and cerebellum, and a slightly lesser extent in neurons in the hypothalamus and hippocampus (at protein level). Also expressed in interneurons in t
  • 数据库链接：

    KEGG: mmu:213760

    STRING: 10090.ENSMUSP00000130967

    UniGene: Mm.259035