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  4. Recombinant Mouse Protein BTG4 (Btg4)

Recombinant Mouse Protein BTG4 (Btg4)

  • 货号：
    CSB-YP002866MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP002866MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP002866MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP002866MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP002866MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Btg4
  • Uniprot No.：
  • 别名：
    Btg4; Pc3bProtein BTG4; BTG family member 4; Protein PC3b
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-250
  • 氨基酸序列
    MRDEIATAVF FVTRLVKKHE KLSTQQIETF ALKLMTILFE KYRGHWHPDC PSKGQAFRCI RINNNENKDP VLERACAESN VNFFHLGLPK EMTIWVDPYE VCCRYGEKKH PFTIASFKGR WENWELAQHV SCAVNRATGD CSSGTSSDEE SCSREAQIIP KVNNPKSVYQ VENFKQSLQP WFCLPRRKHL ADGRGFLPGA ACHPVPKSSK WCRPASRRVD RYHWVNAQLF SGQTAPGEPG EEALSSLKQK
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Adapter protein that bridges CNOT7, a catalytic subunit of the CCR4-NOT complex, to EIF4E, and facilitates maternal mRNAs decay during the maturation of oocytes and in the fertilized egg. It is therefore required for the maternal-zygotic transition (MZT), zygotic cleavage and initiation of embryonic development.
  • 基因功能参考文献：
    1. BTG4 is a key regulator for maternal mRNA clearance during mouse early embryogenesis PMID: 27190313
    2. The intrinsic MAP kinase cascade in oocytes triggered translation of Btg4 mRNA stored in fully grown oocytes by targeting the 3' untranslated region, thereby coupling CCR4-NOT deadenylase-mediated decay of maternal mRNA with oocyte maturation and fertilization. PMID: 27065194
    3. study reports that a complex of BTG4 and CAF1 safeguards metaphase II arrest in mammalian eggs by deadenylating maternal mRNAs PMID: 27605379
    4. IF5/BTG4 may be an aging-related gene in epithelial cells PMID: 25660503
  • 蛋白家族：
    BTG family
  • 组织特异性：
    Expressed in oocytes. Expressed in testis and in olfactory epithelium.
  • 数据库链接：

    KEGG: mmu:56057

    STRING: 10090.ENSMUSP00000110074

    UniGene: Mm.431317