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  4. Recombinant Mouse Protein NDNF (Ndnf)

Recombinant Mouse Protein NDNF (Ndnf)

  • 货号：
    CSB-YP807450MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP807450MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP807450MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP807450MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP807450MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Ndnf
  • Uniprot No.：
  • 别名：
    Ndnf; Protein NDNF; Epidermacan; Neuron-derived neurotrophic factor
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    20-568
  • 氨基酸序列
    Q KLPTRDEELF QMQIRDKEFF HDSSVIPDGA EVSSYLFRDT PRRYFFMVEE DNTPLSVTVT PCDAPLEWKL SLQELHEGSS ADGSGDPELL DQQKQQMTDV EGTELFSYKG NDVEYFLSSS SPSGLYQLEL LSTEKDTHFK VYATTTPESD QPYPELPYDP RVDVTSFGRT TVTLAWKPSP TASILKQPIE YCVVINKEHN FKSLCAAETK MNADDAFMVA PKPGLDFNPF DFAHFGFPTD NLGKDRSLLA KPSPKVGRHV YWRPKVDIQK ICIGNKNIFT VSDLKPDTQY YFDVFMVNTN TNMSTAYVGA FVRTKEEAKQ KTVELKDGRV TDVFVKRKGK KFLRFAPVSS HQKVTFFIHS CMDAVQVQVR RDGRLLLSQN VEGIRQFQLR GKPKGKYLIR LKGNRKGASK LKILATTRPS KHAFPSLPED TRIKAFDKLR TCSSVTVAWL GTQERRKFCI YRKEVDGNYS EDQKRREQNQ CLGPDTRKKS EKVLCKYFHS QNLQKAVTTE TIRDLQPGKS YLLDVYVVGH GGHSVKYQSK IVKTRKVC
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Secretory protein that plays a role in various cellular processes. Acts as a chemorepellent acting on gonadotropin-releasing hormone (GnRH) expressing neurons regulating their migration to the hypothalamus. Also promotes neuron migration, growth and survival as well as neurite outgrowth and is involved in the development of the olfactory system. May also act through the regulation of growth factors activity and downstream signaling. Also regulates extracellular matrix assembly and cell adhesiveness. Promotes endothelial cell survival, vessel formation and plays an important role in the process of revascularization through NOS3-dependent mechanisms.
  • 基因功能参考文献：
    1. Intramuscular administration of NDNF ameliorates post-MI remodeling and function in mice by its abilities to reduce myocyte apoptosis and promote neovascularization. PMID: 25654972
    2. NDNF acts as an endogenous modulator that promotes endothelial cell function and ischemia-induced revascularization through eNOS-dependent mechanisms PMID: 24706764
  • 亚细胞定位：
    Secreted.
  • 组织特异性：
    Expressed in brain and spinal cord with no expression detected in heart, kidney or liver. Expressed by neurons but not by astrocytes. In the brain, detected in the cerebrum, cerebellum and olfactory bulbs. In the cerebral cortex, highly expressed in Cajal
  • 数据库链接：

    KEGG: mmu:68169

    UniGene: Mm.211177