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  4. Recombinant Mouse Protein lyl-1 (Lyl1)

Recombinant Mouse Protein lyl-1 (Lyl1)

  • 中文名称：
    小鼠Lyl1重组蛋白
  • 货号：
    CSB-YP013258MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Lyl1重组蛋白
  • 货号：
    CSB-EP013258MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Lyl1重组蛋白
  • 货号：
    CSB-EP013258MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Lyl1重组蛋白
  • 货号：
    CSB-BP013258MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Lyl1重组蛋白
  • 货号：
    CSB-MP013258MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Lyl1
  • Uniprot No.：
  • 别名：
    Lyl1; Lyl-1; Protein lyl-1; Lymphoblastic leukemia-derived sequence 1
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-278
  • 氨基酸序列
    MCPPQARAEV GSAMTEKTEM VCASSPAPAP PSKPASPGPL STEEVDHRNT CTPWLPPGVP VINLGHTRPI GAAMPTTELS AFRPSLLQLT ALGRAPPTLA VHYHPHPFLN SVYIGPAGPF SIFPNSRLKR RPSHSELDLA DGHQPQKVAR RVFTNSRERW RQQHVNGAFA ELRKLLPTHP PDRKLSKNEV LRLAMKYIGF LVRLLRDQTA VLTSGPSAPG SRKPPARRGV EGSARFGAGH RVEAARSQPV LPGDCDGDPN GSVRPIKLEQ TSLSPEVR
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 基因功能参考文献：
    1. Loss of Lyl1 is associated with lung endothelial barrier disruption. PMID: 24532287
    2. Lyl-1 is a pivotal component of a transcriptional program that controls the lymphoid specification and maintenance of early T lineage progenitors PMID: 22772404
    3. results suggest that LYL-1 plays a definite role in erythropoiesis, albeit with different effects in bone marrow specifically regulating basal erythropoiesis, and spleen, controlling stress-induced erythropoiesis PMID: 21420467
    4. Overexpression of Lyl1 is associated with leukemia formation. PMID: 20705338
    5. LYL1 activity is required for the maturation of newly formed blood vessels in adulthood. PMID: 20418284
    6. coregulation of Scl and Lyl1 later during development may explain the mild phenotype of Scl-/- adult HSCs PMID: 17053063
    7. Similar to Tal-1/SCL, Lyl-1 mRNA expression occurs in the developing cardiovascular and hematopoietic systems, however, contrary to tal-1/scl, lyl-1 is not expressed in the developing nervous system. PMID: 17112790
    8. Overexpression of a transcription factor LYL1 induces T- and B-cell lymphoma PMID: 17486074
    9. These results show that expression of Lyl1 or Scl is essential for maintenance of adult hematopoietic stem cell function. PMID: 19200805

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  • 亚细胞定位：
    Nucleus.
  • 数据库链接：

    KEGG: mmu:17095

    STRING: 10090.ENSMUSP00000046010

    UniGene: Mm.4925