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  4. Recombinant Mouse Protein phosphatase 1 regulatory subunit 15B (Ppp1r15b)

Recombinant Mouse Protein phosphatase 1 regulatory subunit 15B (Ppp1r15b)

  • 货号：
    CSB-YP806811MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP806811MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP806811MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP806811MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP806811MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Ppp1r15b
  • Uniprot No.：
  • 别名：
    Ppp1r15b; Protein phosphatase 1 regulatory subunit 15B; Constitutive repressor of eIF2alpha phosphorylation; CReP
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-697
  • 氨基酸序列
    METGTHRARK RPGPRLGSWF RLPFLRRSHA CSSEFPPPSS RQNPGNSALP ERRTRYWTKL LSQLLALLPS LFQKLLLWSQ LFGGLIPTRW LDFAASYSAL RALRGREESA APTVQKSLSS LRLDSSEDLV VSSLDWLEEG LQWQCSSSDL ELKLKAQERA LDSAAPTFLL EQQLWGVELL PSSLQAGLVS HRELDSSSSG PLSVQSLGNF KVVSYLLNPS YLDYLPQLGL RCQSSAGGGQ FVGFRTLTPE SCYLSEDGCH PQPLRAEMSA TAWRRCPPLS TEGLPEIHHL RMKRLEFLQA NKGQELPTPD QDNGYHSLEE EHNLLRMDPQ HCTDNPAQAV SPAADRPEPT EKKPELVIQE VSQSPQGSSL FCELPVEKEC EEDHTNATDL SDRGESLPVS TRPVCSNKLI DYILGGAPSD LEASSDSESE DWGEEPEDDG FDSDGSLSES DVEQDSEGLH LWNSFHSVDP YNPQNFTATI QTAARIAPRD PSDSGTSWSG SCGVGSCQEG PLPETPDHSS GEEDDWEPSA DEAENLKLWN SFCHSEDPYN LLNFKAPFQP SGKNWKGRQD SKASSEATVA FSGHHTLLSC KAQLLESQED NCPGCGLGEA LAGERYTHIK RKKVTFLEEV TEYYISGDED RKGPWEEFAR DGCRFQKRIQ ETEVAIGYCL AFEHREKMFN RLRIESKDLL LYSNVKK
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Maintains low levels of EIF2S1 phosphorylation in unstressed cells by promoting its dephosphorylation by PP1.
  • 基因功能参考文献：
    1. Results highlighted the essential roles played by GADD34 and CReP in regulating mRNA translation during unstressed conditions and following endoplasmic reticulum stress. PMID: 27161320
    2. Ppp1r15a mutant mice are superficially indistinguishable from wild type; Ppp1r15b(-/-) mouse embryos survive gestation but exhibit severe growth retardation and impaired erythropoiesis, and loss of both Ppp1r15 genes leads to early embryonic lethality PMID: 19181853
  • 蛋白家族：
    PPP1R15 family
  • 数据库链接：

    KEGG: mmu:108954

    STRING: 10090.ENSMUSP00000057062

    UniGene: Mm.293628