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  4. Recombinant Mouse Queuine tRNA-ribosyltransferase subunit QTRTD1 (Qtrtd1)

Recombinant Mouse Queuine tRNA-ribosyltransferase subunit QTRTD1 (Qtrtd1)

  • 货号：
    CSB-YP019147MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP019147MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP019147MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP019147MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP019147MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Qtrt2
  • Uniprot No.：
  • 别名：
    Qtrt2; Qtrtd1; Queuine tRNA-ribosyltransferase accessory subunit 2; Queuine tRNA-ribosyltransferase domain-containing protein 1
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-415
  • 氨基酸序列
    MKLSLIKVVN GCRLGKIQNL GKAGDCTVDI PGCLLYTRTG SAPHLTHQTL RNIHGVPGIA QLTLSSLAEH HEVLAEYKKG VGSFIGMPES LFYCSLHDPV TPGPAGYVTS KSVSVWGFGG RVEMTVSKFM AIQEALQPDW FQCLSDGEAS CAETTSIKRA RKSVDRSLLF LDSCLRLQEE SEVLQKSVII GVIEGGDVME ERLRSARETA KRPVGGFLLD GFQGDPAVTE TRLHLLSSVT AELPEDKPRL ICGVSRPDEV LECIERGVDL FESFFPYQVT ERGCALTFTF DCQLNPEETL LQQNGIQEKI KGLDQAKKIE ATGCNQEMTS FEINLKEKKY QEDFDPLVRG CSCYCCKNHT RAYIHHLLMT NELLAGVLLM MHNFEHYFGF FCSIREALKN DTLAQLKELI CRQMF
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
  • 基因功能参考文献：
    1. TGT weakly interacts with the outer mitochondrial membrane possibly through association with Qv1(QTRD1 variant 1), which was found to be stably associated with the organelle PMID: 19414587
  • 亚细胞定位：
    Cytoplasm. Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族：
    Queuine tRNA-ribosyltransferase family, QTRT2 subfamily
  • 组织特异性：
    Expressed in brain, heart, kidney, liver, lung, skeletal muscle, spleen and testis.
  • 数据库链接：

    KEGG: mmu:106248

    STRING: 10090.ENSMUSP00000023387

    UniGene: Mm.275354