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  4. Recombinant Mouse RNA polymerase II elongation factor ELL (Ell)

Recombinant Mouse RNA polymerase II elongation factor ELL (Ell)

  • 中文名称：
    小鼠Ell重组蛋白
  • 货号：
    CSB-YP007608MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Ell重组蛋白
  • 货号：
    CSB-EP007608MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Ell重组蛋白
  • 货号：
    CSB-EP007608MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Ell重组蛋白
  • 货号：
    CSB-BP007608MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Ell重组蛋白
  • 货号：
    CSB-MP007608MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Ell
  • Uniprot No.：
  • 别名：
    EllRNA polymerase II elongation factor ELL; Eleven-nineteen lysine-rich leukemia protein
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    2-602
  • 氨基酸序列
    AALKEARSY GLSCGRVSDG SRVSVFHVKL TDSALKAFES YRAHQDSVSL RPSIRFEGSQ GHISIPQPDC PEEVRAFSFY LSNIGRDSPQ GSFDCIQQYV SSYGDVHLDC LGSIQDKVTV CATDDSYQKA RQSMAQAEEE TRSRSAIVIK AGGRYMGKKV QFRKPAPGAA DAVPSRKRAT PINLASAIRK SSGSGASSVV QRPFRDRVLH LLALRPYRKA ELLLRLQKDG LTQADKDTLD SLLQQVASVN PKDGTCTLQD CMYKSLQKDW PGYSEGDRQL LKRMLMRKLC QPQNATTDSS PPREHGRSAS PSQKRPTDFI DPLASKKPRI SHFTQRAQPT LNGKLGAPNG HETLLPAPGP TPSDTLSSSH LPPRLEPPRT HDPLADVSND LGHSTQDYKH QEATPAPAPH LGLPLLTDFP QAEQPTSSSH THSRPKKKSK KHKDKERPPE ERPPAPQPDA PTAPALPPDA PGLNGACDNE PTSSSETPDY LLKYPAISSS EQRQSYKNDF NAEYSEYRSL HARIEQITRR FTQLDAQLRQ LSQGSDEYET TRGQILQEYR KIKKTNTNYS CEKRRCEYLH RKLAHIKRLI AEYDQRQLQA WP
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Specifically required for stimulating the elongation step of RNA polymerase II- and III-dependent snRNA gene transcription. ELL also plays an early role before its assembly into in the SEC complex by stabilizing RNA polymerase II recruitment/initiation and entry into the pause site. Required to stabilize the pre-initiation complex and early elongation. Specifically required for stimulating the elongation step of RNA polymerase II- and III-dependent snRNA gene transcription. Elongation factor component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III.
  • 亚细胞定位：
    Nucleus. Nucleus speckle. Nucleus, Cajal body.
  • 蛋白家族：
    ELL/occludin family
  • 数据库链接：

    KEGG: mmu:13716

    STRING: 10090.ENSMUSP00000091163

    UniGene: Mm.271973