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  4. Recombinant Mouse Retinoic acid early-inducible protein 1-epsilon (Raet1e)

Recombinant Mouse Retinoic acid early-inducible protein 1-epsilon (Raet1e)

  • 中文名称：
    小鼠Raet1e重组蛋白
  • 货号：
    CSB-YP887480MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Raet1e重组蛋白
  • 货号：
    CSB-EP887480MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Raet1e重组蛋白
  • 货号：
    CSB-EP887480MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Raet1e重组蛋白
  • 货号：
    CSB-BP887480MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Raet1e重组蛋白
  • 货号：
    CSB-MP887480MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    Raet1e; Retinoic acid early-inducible protein 1-epsilon; RAE-1-epsilon
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    29-227
  • 氨基酸序列
    LD DAHSLRCNLT IKDPTSADLP WCDVKCSVDE ITILHLNNIN KTMTSGDPGK MANATGKCLT QPLNDLCQEL RDKVSNTKVD THKTNGYPHL QVTMIYPQSQ GQTPSATWEF NISDSYFFTF YTENMSWRSA NDESGVIMNK WKDDGDLVQQ LKYFIPQCRQ KIDEFLKQSK EKPRSTSRSP SITQLTSTSP LPPPSHS
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Acts as a ligand for KLRK1.
  • 基因功能参考文献：
    1. Study reports that retinoic acid early induced transcript-1-d and retinoic acid early induced transcript-1-e (Raet1) genes are induced early upon experimental autoimmune encephalomyelitis onset and reach a maximal expression at the peak of the pathology. Study also shows that macrophages as well as microglia, are cellular sources of Raet1 transcripts. PMID: 27444966
    2. CD4(+) NKG2D(+) T cells induce NKG2D down-regulation in natural killer cells in CD86-RAE-1epsilon transgenic mice. PMID: 24708417
    3. Reveal Raet1e, a major histocompatibility complex class 1-like molecule expressed in lesional aortic endothelial cells and macrophage-rich regions, as a novel atherosclerosis gene. PMID: 23948654
    4. Raet1e genes are directly transcriptionally activated by E2F family transcription factors, which play a central role in regulating cell cycle entry. PMID: 23166357
    5. RAE1 expression was sufficient to induce the recruitment of adoptively transferred CTLs to islets. PMID: 22244846

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  • 亚细胞定位：
    Cell membrane; Lipid-anchor, GPI-anchor.
  • 蛋白家族：
    NKG2D ligand family
  • 数据库链接：

    KEGG: mmu:379043

    STRING: 10090.ENSMUSP00000066627

    UniGene: Mm.439724