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  4. Recombinant Mouse Rho GDP-dissociation inhibitor 3 (Arhgdig)

Recombinant Mouse Rho GDP-dissociation inhibitor 3 (Arhgdig)

  • 货号：
    CSB-YP720288MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP720288MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP720288MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP720288MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP720288MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    Arhgdig; Gdi5Rho GDP-dissociation inhibitor 3; Rho GDI 3; Rho-GDI gamma; Rho-GDI2
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-225
  • 氨基酸序列
    MLGLDACELG EQLLELLRLA LCARVLLADK DGESTPSDEV LDEIVPEYQA PGKKSMLAIW QLDPGDVSLV KYKQALLGPL PPIMDPSLPN VQVTRLTLLT EQAPGPIIMD LTGDLDALKN QVFVLKEGIE YKVKITFKVN KEIVSGLKCL HHTYRRGLRV DKAIFMVGSY GPRAQEYEFV TSVEEAPRGA LARGLYVVRS LFTDDDRLNH LSWEWHLHVC QDWKD
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Inhibits GDP/GTP exchange reaction of RhoB. Interacts specifically with the GDP- and GTP-bound forms of post-translationally processed Rhob and Rhog proteins, both of which show a growth-regulated expression in mammalian cells. Stimulates the release of the GDP-bound but not the GTP-bound RhoB protein. Also inhibits the GDP/GTP exchange of RhoB but shows less ability to inhibit the dissociation of prebound GTP.
  • 基因功能参考文献：
    1. RhoGDI2 is required for PKB and CREB activation and cdc42 expression in astrocyte migration after kainic acid-mediated excitotoxic lesion in mouse brain. PMID: 25274045
    2. Our results indicate that the overexpression of Rho-GDIgamma maintains Neural stem cells in the stem cell state preventing migration PMID: 23996536
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    Rho GDI family
  • 组织特异性：
    Detected only in brain, lung, kidney and testis.
  • 数据库链接：

    KEGG: mmu:14570

    STRING: 10090.ENSMUSP00000025019

    UniGene: Mm.1383