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  4. Recombinant Mouse Scrapie-responsive protein 1 (Scrg1)

Recombinant Mouse Scrapie-responsive protein 1 (Scrg1)

  • 中文名称：
    小鼠Scrg1重组蛋白
  • 货号：
    CSB-YP526023MO
  • 规格：
    ￥1836
  • 图片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他：

产品详情

  • 纯度：
    Greater than 90% as determined by SDS-PAGE.
  • 基因名：
    Scrg1
  • Uniprot No.：
  • 别名：
    Scrg1; Scrapie-responsive protein 1; Scrapie-responsive gene 1 protein; ScRG-1
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full Length of Mature Protein
  • 来源：
    Yeast
  • 分子量：
    11.0kDa
  • 表达区域：
    21-98aa
  • 氨基酸序列
    MPSSRLSCYRKLLKDRNCHNLPEGRADLKLIDANVQHHFWDGKGCEMICYCNFSELLCCPKDVFFGPKISFVIPCNNH
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 6xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Tris-based buffer,50% glycerol
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 产品描述：

    The recombinant Mouse Scrg1 protein is encoded by the gene of Scrg1 (21-98aa). The gene of Scrg1 was cloned in a system (Yeast) that supported the expression of Scrg1 and translation of messenger RNA. Modification of Scrg1 by recombinant DNA technology could lead to the expression of the target protein. The protein was fused with N-terminal 6xHis tag in the production. The purity is 90% determined by SDS-PAGE.

    Scrg1 is a protein coding gene that encodes Scrapie-responsive protein 1. According to some studies, Scrg1 may have the following features.
    The protein SCRG1 secreted by hMSCs and its receptor BST1 are positive regulators of self-renewal, migration and osteogenic differentiation. Scrg1 is induced in TSE and brain injury and is associated with autophagy. SCRG1 is a potential marker of autophagy in TSE. Inhibition of linc-SCRG1 may be a novel therapeutic approach to inactivate hematopoietic stem cells and attenuate human liver fibrosis. SCRG1 is involved in cell growth inhibition and differentiation during DEX-dependent chondrogenesis. SCRG1 inhibits LPS-induced CCL22 production via activation of ERK1/2 in mouse macrophage Raw264.7 cells. Linc-SCRG1 acts as a ceRNA for miR26a to depress SKP2 and accelerates hepatocellular carcinoma progression.

  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 基因功能参考文献：
    1. Scrg1 is associated with the secretory pathway of neuronal cells. PMID: 14622145
    2. Taken together, our results indicate that Scrg1 is associated with neurodegenerative processes in TSE, but is not directly linked to dysregulation of prion protein. PMID: 16029203
  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    SCRG1 family
  • 数据库链接：

    KEGG: mmu:20284

    STRING: 10090.ENSMUSP00000034023

    UniGene: Mm.12886